Differential methylation in CITED4, as measured in blood, appears to be a promising marker of bladder cancer susceptibility in women.
At the 2018 Miami Breast Cancer Conference, Dr. Patrick Borgen presented information related to gene expression profiling as a tool for managing DCIS.
A registry study suggests that there may be a familial association between ovarian and testicular cancers.
The combination of selumetinib with dacarbazine did not offer improved survival outcomes over placebo/dacarbazine in patients with metastatic uveal melanoma.
A 56-year-old man presents with a subcutaneous soft tissue mass in the right leg. The patient does not have any other pertinent clinical history. What is your diagnosis?
A thyroid nodule is found in a 43-year-old man and a biopsy is obtained. What is your diagnosis?
Which agents are associated with increased risk of sarcomas in childhood leukemia? What are the most common secondary cancers among survivors of childhood leukemias, lymphomas, and other childhood malignancies? Take this multiquestion quiz to find out.
A 23-year-old woman presents with cervical lymphadenopathy and a biopsy is obtained. What is your diagnosis?
A 43-year-old woman presents with symptoms of dyspnea, wheezing, and shortness of breath. Diagnostic imaging reveals a tumor mass partially obstructing the bronchus of the left lung. What is your diagnosis?
Abiraterone plus prednisolone/prednisone, or docetaxel, combined with ADT may be the most effective therapies for metastatic hormone-naive prostate cancer.
The NCCN has released new clinical practice guidelines for the management of cancer in people living with HIV.
The kinase inhibitor fruquintinib offered improved outcomes vs placebo as a third- and fourth-line treatment in advanced non–small-cell lung cancer.
A large study found no association between the use of metformin or statins and the incidence of ovarian cancer in women with type 2 diabetes.
Response and Development of Immune-Related Adverse Events in an 83-Year-Old Man With Metastatic Urothelial Cancer
An 83-year-old man was diagnosed with multiple low-grade transitional cell carcinomas over a 6-year period. A surveillance cystoscopy in year 7 showed high-grade noninvasive papillary urothelial carcinoma in the bladder trigone. A CT urogram showed a soft-tissue mass with diffuse enhancement in the lower pole of the left kidney, concerning for malignancy.
During the 2018 Miami Breast Cancer Conference, Dr. Sara Hurvitz discussed current management options for patients with early-stage HER2-positive breast cancer.