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A 53-year-old man treated for squamous cell carcinoma of the anus presents 4 weeks post-treatment with a 2-cm anal mass. What is the most appropriate next step in his management?

Men with high midlife cardiorespiratory fitness have a lower incidence of lung and colorectal cancer; however, this association was not seen for prostate cancer.

A combination of biomarkers has shown promise as a surrogate for survival in clinical trials of metastatic castration-resistant prostate cancer.

Women who received cognitive behavioral stress management after surgery for early breast cancer reported better quality of life and lower symptoms of depression.

The FDA requires a risk label on GnRH agonists that indicates the increased risk of cardiovascular disease and diabetes in prostate cancer patients.

In this interview we discuss the current guidelines for lymph node staging in breast cancer and dive into the debate surrounding sentinel node biopsies.

The risk of bone metastases from GISTs, though rare, should be considered during long-term follow-up of patients, especially in those with liver metastases.

The use of intraperitoneal chemotherapy for the treatment of advanced ovarian cancer resulted in a survival benefit over intravenous chemotherapy.

A retrospective analysis showed that crizotinib is highly active in lung cancer with ROS1 rearrangements, which are present in about 1% of lung adenocarcinomas.

Advanced melanoma patients who progressed on ipilimumab were more likely to achieve an objective response when treated with nivolumab than with chemotherapy.

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