A large study found no association between the use of metformin or statins and the incidence of ovarian cancer in women with type 2 diabetes.
Response and Development of Immune-Related Adverse Events in an 83-Year-Old Man With Metastatic Urothelial Cancer
An 83-year-old man was diagnosed with multiple low-grade transitional cell carcinomas over a 6-year period. A surveillance cystoscopy in year 7 showed high-grade noninvasive papillary urothelial carcinoma in the bladder trigone. A CT urogram showed a soft-tissue mass with diffuse enhancement in the lower pole of the left kidney, concerning for malignancy.
During the 2018 Miami Breast Cancer Conference, Dr. Sara Hurvitz discussed current management options for patients with early-stage HER2-positive breast cancer.
This article will discuss the approach to and management of both treatment-related and non–treatment-related nausea and vomiting in cancer patients.
Late last year, ONCOLOGY hosted a writing contest on CancerNetwork.com, in which we asked our readers to share their personal experiences with delivering bad news. The essay below, by Dr. Eileen Parkes from Queen’s University Belfast, United Kingdom, was selected as the first place winner.
Immunotherapy Plus Stereotactic Radiosurgery: Building on the Promise of Precision Medicine for CNS Malignancies—PART 2: Existing Experience and Considerations for Future Trials
In Part 2 of this two-part series, we review the clinical evidence in support of combining immunotherapy with stereotactic radiosurgery for the treatment of brain metastases; examine controversies regarding radiation dose and fractionation, as well as temporal sequencing of multimodality treatment; and discuss future directions in combined therapy.
The first article in this two-part series will provide an overview of both past and present therapeutic vaccination strategies for the promotion of antitumor immunity against prostate cancer.
Here we summarize the available genomic and genetic tests for melanoma, and the level of evidence supporting each of these. We also discuss the current impact of genomic sequencing on the management of melanoma, as well as roles it may play in the near future.
Using CRISPR/Cas9 gene editing to remove CD7 from healthy T cells, researchers have found a way to use third party T cells for CAR-T therapy in T-cell hematologic malignancies.
Researchers have discovered that AML cells require high levels of cholesterol for survival, so the cholesterol pathway could represent a potential therapeutic option for the disease.
During the 2018 Miami Breast Cancer Conference, Dr. Elizabeth A. Mittendorf discussed immunotherapy concepts and strategies related to breast cancer.
Lisinopril and carvedilol reduced cardiotoxicity in patients with HER2-positive breast cancer treated with trastuzumab and anthracyclines.
STING (stimulator of interferon genes) inhibitors have been shown to help T cells thrive and work synergistically with other cancer therapies, so new trials are underway to test whether they can be used to improve response in certain patients.
Substantial variation in treatment patterns can explain geographic differences in survival outcomes in patients with lung cancer, according to a UK study.
How much do you understand about evaluating prognosis and choosing treatment for patients with myeloma? Take our latest quiz to find out.