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A 23-Year-Old Male With Right Leg Pain

  • Cesar A. Moran, MD
Display date: 
Apr 26, 2018

A 23-year-old with no relevant prior medical history presents with pain in the right leg. What is your diagnosis?

Married Melanoma Patients Present at an Earlier Stage

  • Dave Levitan
Apr 26, 2018

Melanoma patients who are married tend to present at earlier stages of the disease than those who are not married, divorced, or widowed; marital status was also associated with the likelihood of undergoing SLNB.

Small-Molecule TKIs Have Potential to Help With Several Malignancies

  • Brian Schwartz, MD
Apr 26, 2018

In this video, Dr. Brian Schwartz highlights several small-molecule TKIs in development with the potential to help patients with several malignancies.

Neoadjuvant Nivolumab Yields High Response in Newly Diagnosed NSCLC

  • Dave Levitan
Apr 25, 2018

Neoadjuvant nivolumab combo proved safe while yielding high response rates in patients with NSCLC.

Whole-Genome Analyses Expand Genetic Picture of Prostate Cancer

  • Dave Levitan
Apr 25, 2018

A study found some mutations that are already targeted by approved or investigational drugs for prostate cancer, along with dozens of targets that should be considered as candidates for future trials.

ctDNA Increase May Predict Regorafenib Response in Advanced CRC

  • Pashalina Kehagias
Apr 25, 2018

In this video, Pashalina Kehagias discusses how an early increase in ctDNA may predict a poor response to regorafenib in advanced CRC.

Novel TKI Plus Chemo Dramatically Shrank Advanced Head & Neck Tumors

  • Anne Landry
Apr 25, 2018

AZD1775, a small-molecule, WEE1-targeting TKI, significantly shrunk tumors when administered in combination with cisplatin and docetaxel in a phase I trial.

Pembrolizumab Plus Chemo Improved Survival in Advanced NSCLC

  • Dave Levitan
Apr 24, 2018

In KEYNOTE-189, a pembrolizumab/chemo combination yielded OS and PFS benefits in patients with advanced NSCLC.

Breast Induration in a 36-Year-Old Woman With Hx of Implants

  • Cesar A. Moran, MD
Display date: 
Apr 24, 2018

A 36-year-old woman presents with history of previous breast implants and induration of the left breast. What is your diagnosis?

Xenograft Platform Could Lead to Mouse-Based Clinical Trials

  • Edison T. Liu, MD
Apr 24, 2018

In this video, Dr. Edison Liu describes a novel patient-derived xenograft platform that might enable development of a mouse-based clinical trials program.

Prognostic Tool Can Guide Extended Endocrine Therapy in ER+ Breast Cancer

  • Dave Levitan
Apr 23, 2018

A simple prognostic tool could be used to identify patients with HR-positive breast cancer who underwent 5 years of endocrine treatment and who might be at higher risk of late distant recurrence.

Forecasting PARP Inhibitor Resistance in Breast Cancer Patients

  • Elizabeth Swisher, MD
Apr 23, 2018

In this video, Dr. Elizabeth Swisher reviews the use of PARP inhibitors in breast cancer, and the importance of understanding how resistance to these agents develops.

A 38-Year-Old Woman With Dyspnea and General Malaise

  • Cesar A. Moran, MD
Display date: 
Apr 23, 2018

A 38-year-old woman with a history of tobacco use presents with shortness of breath, cough, chest pain, and general malaise. What is your diagnosis?

Late Diagnosis: Cause of Poorer Survival in Alcohol-Related Liver Cancer?

  • Anne Landry
Apr 23, 2018

Patients with alcohol-related HCC had worse OS than other HCC patients, mainly due to poorer liver function and more unfavorable tumor characteristics at diagnosis.

Cancer Care Becoming More Patient-Centric

  • Debra Patt, MD
Apr 20, 2018

In this podcast, Dr. Debra Patt discusses trends in cancer care, including how treatments are becoming more personalized and less toxic.

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Oncology Vol 32 No 4
Apr 15, 2018 Vol 32 No 4
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