A 23-Year-Old Male With Right Leg Pain
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Apr 26, 2018A 23-year-old with no relevant prior medical history presents with pain in the right leg. What is your diagnosis?
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Married Melanoma Patients Present at an Earlier Stage
Apr 26, 2018
Melanoma patients who are married tend to present at earlier stages of the disease than those who are not married, divorced, or widowed; marital status was also associated with the likelihood of undergoing SLNB.
Small-Molecule TKIs Have Potential to Help With Several Malignancies
Apr 26, 2018
In this video, Dr. Brian Schwartz highlights several small-molecule TKIs in development with the potential to help patients with several malignancies.
Neoadjuvant Nivolumab Yields High Response in Newly Diagnosed NSCLC
Apr 25, 2018
Neoadjuvant nivolumab combo proved safe while yielding high response rates in patients with NSCLC.
Whole-Genome Analyses Expand Genetic Picture of Prostate Cancer
Apr 25, 2018
A study found some mutations that are already targeted by approved or investigational drugs for prostate cancer, along with dozens of targets that should be considered as candidates for future trials.
ctDNA Increase May Predict Regorafenib Response in Advanced CRC
Apr 25, 2018
In this video, Pashalina Kehagias discusses how an early increase in ctDNA may predict a poor response to regorafenib in advanced CRC.
Novel TKI Plus Chemo Dramatically Shrank Advanced Head & Neck Tumors
Apr 25, 2018
AZD1775, a small-molecule, WEE1-targeting TKI, significantly shrunk tumors when administered in combination with cisplatin and docetaxel in a phase I trial.
Pembrolizumab Plus Chemo Improved Survival in Advanced NSCLC
Apr 24, 2018
In KEYNOTE-189, a pembrolizumab/chemo combination yielded OS and PFS benefits in patients with advanced NSCLC.
Breast Induration in a 36-Year-Old Woman With Hx of Implants
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Apr 24, 2018A 36-year-old woman presents with history of previous breast implants and induration of the left breast. What is your diagnosis?
Xenograft Platform Could Lead to Mouse-Based Clinical Trials
Apr 24, 2018
In this video, Dr. Edison Liu describes a novel patient-derived xenograft platform that might enable development of a mouse-based clinical trials program.
Prognostic Tool Can Guide Extended Endocrine Therapy in ER+ Breast Cancer
Apr 23, 2018
A simple prognostic tool could be used to identify patients with HR-positive breast cancer who underwent 5 years of endocrine treatment and who might be at higher risk of late distant recurrence.
Forecasting PARP Inhibitor Resistance in Breast Cancer Patients
Apr 23, 2018
In this video, Dr. Elizabeth Swisher reviews the use of PARP inhibitors in breast cancer, and the importance of understanding how resistance to these agents develops.
A 38-Year-Old Woman With Dyspnea and General Malaise
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Apr 23, 2018A 38-year-old woman with a history of tobacco use presents with shortness of breath, cough, chest pain, and general malaise. What is your diagnosis?
Late Diagnosis: Cause of Poorer Survival in Alcohol-Related Liver Cancer?
Apr 23, 2018
Patients with alcohol-related HCC had worse OS than other HCC patients, mainly due to poorer liver function and more unfavorable tumor characteristics at diagnosis.
Cancer Care Becoming More Patient-Centric
Apr 20, 2018
In this podcast, Dr. Debra Patt discusses trends in cancer care, including how treatments are becoming more personalized and less toxic.