Several radiographic texture features from the pre-RT CT scan were identified as potential predictors of pCR in rectal cancer patients after neoadjuvant chemoradiation therapy. Future work will focus on validating these features in a larger dataset.
Patients who undergo surgery after chemoradiotherapy demonstrate improved survival; however, this may be related to underlying comorbidities that preclude surgery. IMRT appears to be a reasonable treatment option that may reduce complications from radiotherapy. Careful attention should be given to heart dose during treatment planning.