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A new study found that in patients treated for oropharyngeal cancer, the detection of HPV16 DNA via an oral rinse could be a sign of poor prognosis.

Treatment of CML with various tyrosine kinase inhibitors can induce changes in glomerular filtration rate over time and have other kidney-related effects.

A 44-year-old woman is found to have a large mass in the anterior mediastinum. What is your diagnosis?

A 54-year-old man presents with diffuse peritoneal thickening. What is your diagnosis?

Results of a study suggest that durable survival is possible in melanoma patients treated with MAPK inhibitors, and is perhaps similar to the survival observed with ipilimumab.

Whole-exome sequencing found that mutations of the NF1 gene are an important driver mutation in melanoma, and the third most frequently mutated gene.

A retrospective study was used to develop nomograms predictive of both metastasis-free and overall survival for patients with nonmetastatic osteosarcoma.

A 28-year-old woman with a history of nephrolithiasis has an abdomen CT scan to investigate an abnormality in the liver. What is your diagnosis?

Six carbonyl compounds in exhaled breath can effectively discriminate between lung cancer patients and healthy patients, says a new study.

The FDA approved the proteasome inhibitor carfilzomib for the treatment of multiple myeloma, when used in combination with lenalidomide and dexamethasone.

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