Korean investigators concluded that, in terms of recurrence risk, a qualified high-volume surgeon may be optimal for performing the initial surgery in this setting.
A murine study suggests this engineered combination may offer a major advantage over current CAR T-cell–based immunotherapies.
The CoGAPS gene activity algorithm may elucidate molecular changes that occur as H&N tumors acquire resistance to cetuximab, says a Johns Hopkins team.
An otherwise healthy 38-year-old man presents with an enlarged lymph node in the right side of the neck. Surgical resection of the lymph node is performed. What is your diagnosis?
A set of reproducible biomarkers are associated with better response rates to anti–PD-1 therapy in patients with advanced melanoma.
Oncologists should refer patients who want traditional genetic counseling and/or have preexisting psychosocial factors that would increase risk of an adverse psychological outcome of counseling.
In analyzing over 8,300 mosaic chromosomal alterations in UK Biobank participants, Harvard researchers uncovered specific alterations that may predict for CLL.
A rapid EGFR-specific assay allowed for quicker identification of EGFR mutation–positive NSCLC, and thus a shorter time to initiation of EGFR-directed therapy.
The intratumoral vasculature of high-grade serous ovarian cancer does not appear to undergo significant changes during disease progression.
In a large international study, pre-AML cases had greater clonal expansion and enrichment of specific gene mutations; origins of AML were detected > 5 years before it developed.
Brazilian researchers say their study results “suggest the overall DNA methylation profile may be influenced by the histological subtype of thyroid cancer.”
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The most common presentation among the younger patients was bleeding, and they were more likely have a family history of rectal cancer.
Treatment of high-risk melanoma with adjuvant bevacizumab following resection improves disease-free survival over standard observation, but not overall survival.
Recent use of aspirin or NSAIDs is associated with improved ovarian cancer–specific survival.