The purpose of this study is to describe the outcomes of definitive radiation in medically inoperable early-stage endometrial carcinoma. Although early-stage disease usually results in favorable overall survival (OS) after surgery, there is a growing cohort of patients who are medically inoperable secondary to morbid obesity.
(P049) Simultaneous Integrated Boost–Intensity-Modulated Radiation Treatment in Head and Neck Cancer: Outcomes From a Single-Institution Series
The main aim of this study is to assess the acute and late toxicity as well as clinical outcomes in patients with head and neck cancer treated with SIB-IMRT at a National Cancer Institute (NCI)-designated comprehensive cancer center.
Radiation pneumonitis (RP) is a significant toxicity following thoracic radiotherapy, with no method to predict individual risk. Our lab had previously shown that pulmonary metabolic response rate (PMRR) is highly predictive of RP in lung cancer. In this prospective study, we used PMRR as a surrogate marker to predict radiation-induced lung toxicity in lung cancer patients receiving thoracic radiotherapy.
(S007) Stereotactic Radiosurgery to the Brain With Concurrent BRAF Inhibitors for Melanoma Metastases
Linear accelerator-based stereotactic radiosurgery (SRS) is an effective treatment for selected melanoma patients with brain metastases. Recently, BRAF inhibitors have shown efficacy in stage IV melanoma. We sought to determine the effectiveness of SRS in patients with melanoma who are also being treated with BRAF inhibitors.
(P003) Isolated Port-Site Metastases Following Laparoscopic Hysterectomy for Endometrial Cancer: Outcomes of Patients Treated With Radiotherapy
Laparoscopic hysterectomy is increasingly replacing total abdominal hysterectomy as the standard approach in the management of endometrial cancer. An uncommon but reported complication of this minimally invasive approach is the recurrence of disease at the surgical entry site, known as port- or trocar-site metastasis.
(P048) Quality Assurance Assessment of Diagnostic and Therapy Simulation Computed Tomography Image Registration for Head and Neck Radiotherapy: Anatomic Region of Interest–Based Comparison of Rigid and Deformable Algorithms
The purpose of this study was to develop a workflow process that enables quantitative assessment of different image registration techniques used for head and neck simulation CT to diagnostic CT coregistration.
Effective cancer screening should detect disease at an earlier, more curable stage and thus reduce the incidence of late-stage diagnosis. In the last 3 decades, the Pap smear has become widely practiced in the US and is effective in the early diagnosis and prevention of cervical cancers.
(S006) Extended-Field IMRT With Concomitant Boost for Node-Positive Cervical Cancer: Analysis of Regional Control Rate and Recurrence Pattern
We have been treating patients with positive pelvic nodes with extended-field intensity-modulated radiation therapy (IMRT) to address the PA region prophylactically with a concomitant boost to the involved nodes. The purpose of this study is to assess regional control rates and recurrence patterns with this technique.
The therapeutic index of treating cancer with ionizing radiation (IR) can be increased by minimizing normal tissue toxicity. Unfortunately, the therapies that have been developed to date have had limited efficacy. Therefore, identifying novel targets to protect normal tissue is essential during treatment.
(P142) Complementary and Alternative Medicine in Radiation Oncology Training: From a Resident’s Perspective
Today’s health care system is evolving in its approach to the management of an ethnically diverse population, as it continues to struggle with the imperative of providing cost-effective care. This study attempts to assess the level of knowledge and interest current residents have in CAM teachings, with the goal of eventually incorporating such evidence-based study into training curriculum.