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Colorectal Cancer Surgical Practice Guidelines

Colorectal Cancer Surgical Practice Guidelines

Scope and Format of Guidelines

The Society of Surgical Oncology surgical practice guidelines focus
on the signs and symptoms of primary cancer, timely evaluation of the symptomatic
patient, appropriate preoperative evaluation for extent of disease, and
role of the surgeon in diagnosis and treatment. Separate sections on adjuvant
therapy, follow-up programs, or management of recurrent cancer have been
intentionally omitted. Where appropriate, perioperative adjuvant combined-modality
therapy is discussed under surgical management. Each guideline is presented
in minimal outline form as a delineation of therapeutic options.

Since the development of treatment protocols was not the specific aim
of the Society, the extensive development cycle necessary to produce evidence-based
practice guidelines did not apply. We used the broad clinical experience
residing in the membership of the Society, under the direction of Alfred
M. Cohen, MD, Chief, Colorectal Service, Memorial Sloan-Kettering Cancer
Center, to produce guidelines that were not likely to result in significant
controversy.

Following each guideline is a brief narrative highlighting and expanding
on selected sections of the guideline document, with a few relevant references.
The current staging system for the site and approximate 5-year survival
data are also included.

The Society does not suggest that these guidelines replace good medical
judgment. That always comes first. We do believe that the family physician,
as well as the health maintenance organization director, will appreciate
the provision of these guidelines as a reference for better patient care.


Society
of Surgical Oncology Practice Guidelines: Colorectal Cancer

Symptoms and Signs

    Early-stage disease
  • Change in frequency, consistency, and shape of bowel movements
  • Bleeding: overt or occult
    Advanced-stage disease
  • For colon carcinoma:
  1. Colicky abdominal pain
  2. Abdominal distention, nausea, vomiting
  3. Obstruction/perforation
  4. Palpable or visible mass
  5. Weight loss
  6. Anemia
  • For rectal carcinoma:
    1. Rectal bleeding, mucus discharge
    2. Tenesmus
    3. Rectal pain
    4. Weight loss
    5. Constipation
    6. Diarrhea
    7. Anemia

    Evaluation of the Symptomatic Patient

      Work-up
    • If the patient presents with one episode of bright red blood on toilet
      paper, a rectal examination, proctosigmoidoscopy, and reassurance are all
      that are needed.
    • If the patient has had more than one episode of bleeding, is older
      than age 30, has a family history of colon cancer, has a diagnosis of inflammatory
      bowel disease, has other gastrointestinal symp- toms or a change in bowel
      habits, or is anemic, the following examinations should be performed in
      sequence until a diagnosis is reached:
    1. Rectal examination
    2. Proctosigmoidoscopy and/or flexible sigmoidoscopy with biopsy
    3. Colonoscopy with biopsy (preferred) or double-contrast barium enema
  • If the patient presents with occult bleeding or overt bleeding mixed
    with stools; a change in the frequency, consistency, and shape of bowel
    movements; any of the symptoms of advanced- stage disease, with the exception
    of obstruction or perforation, the following examinations should be performed
    in sequence until a diagnosis is reached:
    1. Rectal examination
    2. Proctosigmoidoscopy and/or flexible sigmoidoscopy with biopsy
    3. Colonoscopy with biopsy (preferred) or double-contrast barium enema
  • When the patient presents with intestinal obstruction:
    1. Examine for peritoneal signs.
    2. An abdominal x-ray (flat and upright) will usually reveal the site
      of the obstruction.
    3. A water-soluble contrast enema will clarify the nature of the obstructing
      lesion.
  • The occurrence of free intestinal perforation is usually confirmed by
    free air under the diaphragm, best demonstrated in an upright chest, upright
    abdominal, or a left decubitus abdominal x-ray.
    • Appropriate timeliness of surgical referral
    • A rectal examination with stool occult blood must be part of the initial
      evaluation.
    • Proctosigmoidoscopy and flexible sigmoidoscopy are office-based procedures
      that require minimal preparation, and one or both procedures can be performed
      at the time of the original visit.
    • A colonoscopy or double-contrast barium enema requires a complete mechanical
      bowel preparation. It should be performed at the patient's earliest convenience.
    • If a barium enema is obtained, it must be complemented by sigmoidoscopy
      or at least rigid proctoscopy.

    Preoperative Evaluation for Extent of Disease

      Physical examination
      Chest x-ray
      CBC and chemistry profile
    • The value of carcinoembryonic antigen is unproven.
      Abdominal CT scan or liver ultrasound (both unproven)
      Rectal cancer
    • Pelvic CT in selected patients
    • Endorectal ultrasound if treatment will be altered by better definition
      of the T-stage.
      Colonoscopy or double-contrast barium enema
    • To evaluate the rest of the colon

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