BETHESDA, MdA large and growing body of data indicate that
exposure to polio vaccines tainted with the simian virus SV40
has not led to an outbreak of mesotheliomas, osteosarcomas, or
ependyomas, the NCI said.
Concern that people who received the original Salk and Sabin polio
vaccines might have an increased risk of cancer first arose in 1960
when researchers found the virus had contaminated monkey kidney cells
used to grow the vaccines. A recent study found traces of SV40 in
human mesothelioma, osteosarcoma, and ependyoma tumors.
NCI scientists reported in 1997 that a 30-year follow-up of a large
number of Americans exposed to the contaminated vaccines found no
increase in these three cancers.