The Science paper, carrying the names of 104 scientists from an
international consortium of genome labs in North America, Europe,
and Japan, reveals the locations of 16,334 genes identified from
among the estimated 50,000 to 100,000 genes that comprise the
human genome. The number of human genes mapped to specific sites
on specific chromosomes has tripled in the last 2 years.
The genes are included in the new map whether or not their function
in the body is known. Indeed, only about 10% of the genes on the
map are fully characterized. The others represent small stretches
of DNA that identify the gene, but which require more information
before researchers can tell what the gene looks like and the protein
for which it codes.
Translated to the Internet by an NLM team led by Mark S. Boguski,
MD, PhD, and Greg D. Schuler, PhD, the map will be updated frequently
to include newly identified genes.
The gene map represents the third of three genomic maps compiled
by the Human Genome Project. The other two, called genetic maps
and physical maps, chart the location of certain molecular markers
that help researchers locate the position of a gene.