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Medarex, Ciba Form Partnership

Medarex, Ciba Form Partnership

ANNANDALE, NJ--Medarex, Inc. and Ciba-Geigy, Ltd. have entered into an alliance for developing and marketing Medarex's MDX-210 Bispecific product. Medarex will be primarily responsible for development through phase II trials, and Ciba will be responsible for phase III trials, regulatory approvals, and commercial launch.

MDX-210 is designed to induce tumor cell killing by simultaneously binding to the HER-2 protein on the cancer cell surface and to a key receptor on immune system killer cells. The product is currently in clinical trials for the treatment of breast, ovarian, prostate, and other tumors.

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