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New Neupogen Formula More Temperature Stable

New Neupogen Formula More Temperature Stable

THOUSAND OAKS, Calif--A new formulation of Neupogen (filgrastim or G-CSF) that contains sorbitol instead of mannitol is now available from Amgen.

The new formulation has the same clinical safety and efficacy profile as the mannitol-containing version, but offers additional flexibility with respect to storage parameters.

Sorbitol-containing Neupogen will remain stable even if exposed to freezing temperatures, as might occur in transit. The recommended storage temperature will continue to be 2° to 8° C. However, the gel tray insulation and freeze watch indicators required with mannitol-containing Neupogen will be eliminated, allowing for smaller packaging and reduced need for refrigerator inventory space.

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