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NSABP to Study Docetaxel in Operable Breast Cancer

NSABP to Study Docetaxel in Operable Breast Cancer

COLLEGEVILLE, Penn--Rhône-Poulenc Rorer Inc. and the National Surgical Adjuvant Breast and Bowel Project (NSABP) have announced the initiation of a new clinical trial (B-27) utilizing docetaxel (Taxotere) in women with operable breast cancer.

Randomization will be into three groups: All groups will first receive four cycles of Adriamycin and cyclophosphamide (AC). After completion of AC, group I will have surgery to remove the local tumor; group II will receive four cycles of docetaxel, followed by surgery; group III will have surgery, followed by four cycles of docetaxel. All groups will take tamoxifen (Nolvadex) for 5 years.

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