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Obesity Outweighs Reflux Disease as Esophageal Cancer Risk

Obesity Outweighs Reflux Disease as Esophageal Cancer Risk

BRISBANE, Australia, Oct. 11 -- Obesity even without reflux disease is associated with six times the risk of developing esophageal adenocarcinoma compared with those of normal weight, researchers here found.

For those with gastroesophageal reflux disease (GERD) without obesity, the esophageal adenocarcinoma risk was five times greater than for those without GERD, they added.

But obesity combined with GERD was associated with a 16 times greater risk of esophageal adenocarcinoma, David C. Whiteman, MBBS, Ph.D., of the Queensland Institute of Medical Research here, and colleagues, reported online in Gut.

Men and those younger than 50 were especially vulnerable to esophageal adenocarcinoma, they reported.

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