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T Cell Diversity in Tumor May Influence Ovarian Cancer Outcomes

T Cell Diversity in Tumor May Influence Ovarian Cancer Outcomes

A new study has found that higher T-cell diversity in ovarian cancer is associated with poor overall survival. Researchers used deep T-cell receptor sequencing to evaluate the clonal composition of tumor-infiltrating lymphocytes in an attempt to identify new prognostic biomarkers in ovarian cancer.

The results of the study (abstract 5546) were presented by Kunle Odunsi, MD, PhD, of the Roswell Park Cancer Institute in Buffalo, New York, at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting, held June 3–7 in Chicago. Here Dr. Odunsi discusses the results of the study and highlights other interesting ASCO studies in gynecologic cancers.

 
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