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Bryant Furlow

Bryant Furlow

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IDH1-mutant gliomas can affect adjacent, nonmalignant cells in ways that trigger seizures, according to research reported at the 21st Annual Scientific Meeting of the Society for Neuro-Oncology.

Four years in the making, the new 2016 World Health Organization Classification of Tumors of the Central Nervous System includes new genetically identified entities and variants, allowing more diagnostic precision, and a new “layered” approach to diagnosis.

Computer analysis of subvisual data extracted from routine clinical MRI exams outperforms human experts at differentiating brain tumor recurrence from radiation necrosis.

Caring for patients with brain tumors can have marked effects on the well-being of oncology clinicians, frequently leading to burnout, and authors of an ongoing survey study aim to get a clearer picture of those impacts.

The anti-inflammatory ibudilast shows early preclinical promise against glioblastoma cell lines when combined with temozolomide, according to new research.

Several FDA-approved anti-malarial and anti-fungal drugs might be able to overcome a previously unexploited mechanism that allows some leukemia cells to escape programmed cell death.

Memorial Sloan Kettering Cancer Center’s experience shows that selected patients with low-risk papillary thyroid cancer can safely defer surgery in favor of active surveillance.

Dual inhibition of PI3K signaling and histone deacetylase 2 (HDAC2) enzymes with CUDC-907 slowed thyroid tumor cell proliferation, tumor progression and metastasis, according to a preclinical study.

The risk of immunotherapy-related destructive thyroiditis requires close patient monitoring and can cause permanent hypothyroidism.

Mitochondrial glycerophosphate dehydrogenase (mGPDH) is overexpressed in differentiated thyroid cancer (DTC) tissue, and metformin, which downregulates mGPDH, is associated with slowed growth in metastatic DTC tumors in mice.

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