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Bosutinib a Good Fourth-Line Option in CML
A small retrospective study of heavily pretreated patients with chronic myeloid leukemia found bosutinib to be a good option in the fourth-line setting.
Bone Metastases in Gastrointestinal Stromal Tumors
The risk of bone metastases from GISTs, though rare, should be considered during long-term follow-up of patients, especially in those with liver metastases.
FDA Approves Dinutuximab (Unituxin) for Pediatric Neuroblastoma
The US Food and Drug Administration has approved dinutuximab (Unituxin) for the treatment of high-risk neuroblastoma in pediatric patients.
FDA Approves First Biosimilar, Filgrastim-sndz (Zarxio)
The US Food and Drug Administration has approved filgrastim-sndz (Zarxio), a biosimilar of filgrastim (Neupogen), and the first such agent to be approved in the United States.
FDA Approves Nivolumab (Opdivo) for NSCLC
The FDA has approved nivolumab (Opdivo) for the treatment of metastatic squamous non-small-cell lung cancer (NSCLC) in patients who have progressed on a platinum-based chemotherapy.
FDA Approves Panobinostat for Multiple Myeloma
The FDA has approved panobinostat (Farydak), in combination with bortezomib and dexamethasone, for treating patients with multiple myeloma.
RT Effective for Palliation of Bone Metastases From HCC
A recent study found that radiation therapy was effective for the palliation of painful spinal metastases in patients with hepatocellular carcinoma.
FDA Approves Lenvatinib for Thyroid Cancer
The FDA has approved lenvatinib (Lenvima) for the treatment of patients with progressive, differentiated thyroid cancer refractory to radioactive iodine.
Pelareorep Gets FDA Orphan Drug Nod for Ovarian Cancer
The US Food and Drug Administration has granted Orphan Drug Designation to pelareorep (Reolysin) for the treatment of ovarian cancer.
FDA Approves Palbociclib for Advanced Breast Cancer
The FDA has approved the CDK4/6 inhibitor palbociclib (Ibrance) for the treatment of postmenopausal women with metastatic breast cancer.