Vorinostat Plus Bevacizumab Had Activity in Previously Treated RCC
Using the HDAC inhibitor vorinostat plus the VEGF inhibitor bevacizumab resulted in clinical activity in patients with clear cell renal cell carcinoma.
Relief From Painful Bone Mets Possible at Day 10 of Radiotherapy
Men with painful bone metastases from prostate cancer may be able to achieve clinically meaningful improvements in pain and quality of life as early as 10 days after undergoing radiotherapy.
Clofarabine Consolidation May Improve RFS in Younger AML Patients
Three courses of clofarabine combined with cytarabine may improve relapse-free survival in patients with acute myeloid leukemia in first remission.
Feasible for Patients to Self-Report Adverse Events in Clinical Trials
Patients participating in cancer clinical trials were willing and able to report symptomatic adverse events and reported more events than investigators did.
Younger Cancer Survivors Reduced Prescription Drug Use for Financial Reasons
Many non-elderly cancer survivors may change their use of prescription drugs, such as skipping doses or requesting cheaper medications, for financial reasons.
Site of Cancer Care Affected Outcomes for AYAs With Leukemia
Adolescents and young adults with leukemia experienced inferior outcomes compared with children, especially if they were treated outside of a specialized cancer center.
Use of Ugly Duckling Sign Could Improve Efficiency of Melanoma Detection
The identification of ugly duckling nevi using a whole-body skin examination for intrapatient comparative analysis improves accuracy of melanoma detection.
Heat Shock Protein Vaccine Elicited Immune Response in Glioblastoma
The addition of an autologous tumor derived–heat shock protein vaccination to standard therapy may improve outcomes for patients with glioblastoma.
Pathology Aids in Diagnosis of Hereditary Leiomyomatosis, RCC
Suspicious pathology from kidney tumors was significantly associated with testing positive for fumarate hydratase mutations, which may aid in the early diagnosis of hereditary leiomyomatosis and renal cell carcinoma.
Lifetime Weight Gain Linked With Risk for Esophageal, Gastric Cancer
Overweight individuals in early adulthood who gained additional weight to become obese later in life are at an increased risk for esophageal and gastric cardia adenocarcinomas.
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