Immunotherapy Combination Promising in Advanced Melanoma
The combination of an intratumoral injection of CVA21 and ipilimumab has demonstrated durable response with minimal toxicity in patients with advanced melanoma.
Low Disease Burden Improved Durability of CAR T-Cell Therapy in B-ALL
Low pretreatment disease burden improved durability of CAR T-cell therapy in patients with relapsed B-cell acute lymphoblastic leukemia.
Smoking Linked With Worse Pancreatic Cancer Survival
Cigarette smoking was associated with an almost 40% reduction in survival among patients with pancreatic cancer.
Adiponectin Signaling May Explain “Obesity Paradox” of RCC
BMI was inversely correlated with serum adiponectin levels in RCC, and low BMI and high adiponectin might be associated with disease aggressiveness and survival in patients with the disease.
Pacritinib Induced Reduction in Splenomegaly, Myelofibrosis Symptoms
The JAK2 and FLT3 inhibitor pacritinib induced significant and sustained spleen volume reduction and symptom reduction in patients with myelofibrosis.
Relapsed, Refractory Myeloma Has Indirect Societal Costs
Patients with relapsed or refractory multiple myeloma experienced significant indirect social costs from their disease, in addition to the direct costs.
Adjuvant TKI Use in High-Risk Clear Cell RCC Not Effective
Updated results of the ASSURE trial showed that adjuvant sunitinib or sorafenib did not improve disease-free survival among high-risk patients with renal cell carcinoma.
FDA Warns of Rare Cancer Linked to Breast Implants
The FDA has recently released a statement identifying a new rare T-cell lymphoma caused by breast implant surgery.
ASCO Statement Opposes Trump’s Recommended Budget Cuts to NIH
ASCO has released a statement announcing its opposition to President Trump’s budget outline for FY2018, which would cut about $6 billion in funding to the National Institutes of Health.
Short-Course RT With Delayed Surgery Viable in Rectal Cancer
No difference in time to recurrence, recurrence-free survival, or overall survival were noted for patients with rectal cancer who underwent one of three different preoperative radiotherapy regimens.
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