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Prenatal Vitamins May Fend Off Some Childhood Brain Tumors

Neil Osterweil
Reviewed by Zalman S. Agus, MD; Emeritus Professor at the University of Pennsylvania School of Medicine. | September 21, 2006
  • Explain to interested patients that this study claims to have found a link between use of vitamin supplements and diets high in iron and folate during the periconception period and a lower risk for certain childhood brain tumors.

  • Explain that good diet and nutrition, possibly including prenatal vitamin supplements, are essential to the health of developing fetuses and can prevent neural tube defects such as spina bifida.

PHILADELPHIA, Sept. 21 -- Epidemiologists have associated vitamins taken by women around the time of conception and in early pregnancy and the risk of brain cancer for their children.

Mothers of children with medulloblastomas or primitive neuroectodermal tumors of the brain were less likely than mothers of unaffected children to have taken prenatal multivitamins, found Greta R. Bunin, Ph.D., of Children's Hospital of Philadelphia, and colleagues at St. Jude's Children's Research Hospital in Memphis.

The mothers of children with brain tumors also tended to have diets lower in folate and iron, they noted in the September issue of Cancer Epidemiology Biomarkers & Prevention.

But the mothers' consumption of cured meats did not appear to influence risk for brain tumors in children, the authors added. The meats have been implicated as a possible cause of brain tumors because they contain nitrates and nitrosamines that can induce nervous system tumors in animals.

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