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Brain Tumors

Current and Emerging Treatments for Brain Metastases

Jenny Lin, BA, Rahul Jandial, MD, PhD, Amanda Nesbit, BS, et al; ONCOLOGY Vol. 29; No. 4
Conventional methods for treating brain metastasis, such as surgery, WBRT, and SRS, each compete with and complement one another. A plethora of recent studies have helped define and expand the utility of these tools.

Brain Tumors

Gross total resection was associated with significantly lower all-cause mortality in patients with atypical and malignant meningioma, according to a new study.

Often excluded from early trials, adults with high-grade gliomas may be good candidates for solid tumor phase I studies of single agents, according to a new analysis.

Whole brain radiation therapy helps control tumor growth in patients with 1 to 3 small brain metastases, but it does not significantly extend patient survival.

Meningiomas are the most common primary brain tumor and comprise nearly one-third of all newly diagnosed primary brain tumors.

Childhood cancer patients treated with brain irradiation may be at a higher risk for developing into obese adults, according to a new study.

Conventional methods for treating brain metastasis, such as surgery, WBRT, and SRS, each compete with and complement one another. A plethora of recent studies have helped define and expand the utility of these tools.

Some targeted systemic therapies have demonstrated evidence of activity in the brain—specifically in melanoma, lung cancers, and breast cancers—and these agents warrant further study in clinical trials.

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