RESEARCH REPORT Dave Levitan The combination of whole-brain radiation therapy and the EGFR inhibitor erlotinib showed a promising response rate and was well tolerated in a new phase II trial of patients with brain metastases from non-small-cell lung cancer.
REVIEW ARTICLE Elgene Lim, Nancy U. Lin;ONCOLOGY Vol. 26 No. 7 This review will focus on the breast cancer subtypes with the highest incidence of breast cancer brain metastases and will characterize differences in the clinical behavior of brain metastases that arise from these different subtypes.
The development of metastatic disease in patients with paraganglioma is an unusual and challenging event. This case report and review describes the specific features of this disease and the multiple therapeutic options.
• An Uncommon Manifestation of an Uncommon Disease
The authors address several commonly cited beliefs that have hindered the development of therapeutic agents for central nervous system malignancies, and advance reasons that they feel justify including patients with brain metastases in clinical trials of new therapeutic approaches for lung cancer.
• Lung Cancer-Related Brain Metastases: Further Considerations
The first three months after standard radiation therapy for a brain tumor must be hell for patients and their families. The established MacDonald... More »
A 16-year-old boy with a history of leukemia at age 12 years complains of right hip pain of several months' duration. A 34-year-old woman who had... More »
Survivors of childhood cancer frequently present to primary care practitioners for a routine physical examination or for urgent care. Knowledge of the... More »
Any fluid-filled cavity or sac that is lined by an epithelium is a cyst, and intracranial cystic lesions are a common finding on CT and MR imaging of... More »
Incidental findings in brain MR imaging of asymptomatic subjects show a high prevalence of low-risk meningiomas and small aneurysms. Researchers... More »
A healthy 24-year-old male presented with a history of several months of poorly localized headaches and blurred vision. MRI of the brain demonstrated a multi-lobulated mass. Based on the radiographic appearance of the mass, what is the most likely diagnosis?
Five Steps to Improving Patient Access Judy Capko, May 21, 2013 Patient access is getting increased attention through reform initiatives. Here are five steps you can take to make sure patients get appropriate access to care in your office.
Growing HIPAA Threat – Ignore Windows XP at Your Own Peril Marion K. Jenkins, May 21, 2013 Chances are good that you have some major ticking software time bombs lurking in your medical practice's computer environment, namely Windows XP and Server 2003.
Three Areas to Reduce Costs at Your Medical Practice Greg Mertz, May 19, 2013 By taking a hard look at reducing costs for staffing, overhead, and technology at your medical practice, you may see increased physician compensation.
Dos and Don’ts for Starting a Physician Blog Michael Woo-Ming, MD, May 18, 2013 Starting a physician blog can provide your medical practice with marketing benefits, but it's important to do it right.
Although important questions still remain regarding chemotherapy choice, sequence, and dosing, the answers to which will require additional large phase III trials, radiotherapy alone is no longer appropriate therapy for 1p/19q codeleted anaplastic oligodendrogliomas.
Here we present the history, staging system, and treatment of medulloblastoma, reviewing the prognostic value and clinical application of molecular subtyping while highlighting the differences between adult and pediatric disease.
This review will focus on the breast cancer subtypes with the highest incidence of breast cancer brain metastases—HER2-positive breast cancer, and triple-negative breast cancer—and will characterize differences in the clinical behavior of brain metastases that arise from these different subtypes.
The development of metastatic disease in patients with paraganglioma is an unusual and challenging event. This case report and review describes the specific features of this disease and the multiple therapeutic options.
The authors address several commonly cited beliefs that have hindered the development of therapeutic agents for central nervous system malignancies, and advance reasons that they feel justify including patients with brain metastases in clinical trials of new therapeutic approaches for lung cancer.
A healthy 24-year-old male presented with a history of several months of poorly localized headaches and blurred vision. MRI of the brain demonstrated a multi-lobulated mass. Based on the radiographic appearance of the mass, what is the most likely diagnosis?
