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Home » Breast Cancer

CASE STUDY 

Ductal Carcinoma in Situ

By Stamatia Destounis, MD1 | May 5, 2011
1Managing Partner, Radiologist, Elizabeth Wende Breast Care, Rochester, NY

Clinical History

A 57-year-old patient presents for evaluation of right nipple discomfort. The patient has family history of a mother and sister with premenopausal breast cancer.

Findings

Digital mammography shows area of calcifications (Figure 1a-b). Magnification views demonstrate intraductal pleomorphic microcalcifications in the right 11:00 area (Figure 1c).

No noted findings on physical exam or ultrasound.

Diagnosis

Vacuum assisted stereotactic needle core biopsy of the right breast 11:00 microcalcifications reveals ductal carcinoma in situ.

FIGURE 1A
FIGURE 1B
FIGURE 1C
FIGURE 2A

FIGURE 2B

MRI imaging performed for extent of disease demonstrates linear beaded enhancement extending from nipple posteriorly for 8cm within the right breast upper outer quadrant (Figure 2a-b).  

Discussion

This case demonstrates the benefit of multimodality imaging including digital mammography and breast magnetic resonance imaging (MRI) in this patient, which led to a diagnosis of ductal carcinoma in situ (DCIS). There has been some conflicting information in the literature regarding MRI and its usefulness in the evaluation of DCIS. For this patient, the MRI revealed the extensive area of involvement more so than mammography. This information was critical to the surgeon for surgical planning.

This article was originally published at Diagnostic Imaging

 

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by melinda fawbush,msn, arnp | May 18, 2011 2:27 PM EDT

While not the focus of this article, this family should be tested for hereditary breast and ovarian cancer syndrome because of the two cases of premenopausal breast cancer and now the case of postmenopausal DCIS. The preferable one to be tested first would be the mother or sister who were diagnosed at a younger age.

by Jondavid Pollock | May 18, 2011 2:14 PM EDT

How often does the surgeon truly benefit from an MRI for treatment planning purposes? Of all of the proposed instances wherein MRI appears to have some advocates, the treatment planning argument hasn't received much press. Indeed, as a radiation oncologist who favors partial breast irradiation, I would surmise that a pre-implant breast MRI would be edifying to rule out the presence of multicentric disease. That being said, none of the rad oncol organizations (ASTRO or ABS) favors this modality for radiotherapy planning. Comments or thoughts?






 
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