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Cancer and Genetics

Cancer and Genetics

A new study at a single center in Japan found no significant differences in the rate of BRCA mutations between ovarian cancer patients with or without family histories of the mutations and recommends that BRCA1/2 testing be required for all ovarian cancer patients

A new genetic analysis found five new genetic variants that raise the risk for gliomas. One of the five was associated with a sharply increased risk for glioblastoma.

A basket trial of patients with various nonmelanoma BRAF-mutated cancers has shown that additional tumor types may also be responsive to vemurafenib.

Breast cancer patients with PIK3CA gene mutations may not benefit from dual anti-HER2 inhibition, according to a new study in The Oncologist.

By exploring gene expression variables in addition to clinicopathologic variables, researchers were able to better predict which melanoma patients would have sentinel lymph node biopsy positivity.

Patients with acute myeloid leukemia who had a DNMT3A mutation had poorer disease prognosis, according to an analysis of patients aged 60 years or younger.

Genotyping of African Americans suggest that with regard to somatic driver mutations in non-small-cell lung cancer (NSCLC), black patients do not significantly differ from white patients, according to a new study.


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