The chemotherapeutic agents included in this Appendix are classified by mechanism of action and are organized as follows:
• alkylating agents;
• antimetabolites;
• natural products;
• targeted agents
– monoclonal antibodies
– molecularly targeted therapies
FDA-approved uses and dose-limiting effects are set in italic type for emphasis. For a complete discussion of these mechanisms of action, see chapter 3 on “Principles of oncologic pharmacotherapy.”
FIGURE: Targeted therapies: Monoclonal antibodies
FIGURE: Molecularly targeted therapies
