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Home » Cancer Management: A Multidisciplinary Approach

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CANCER MANAGEMENT: ONLINE EDITION 

Fatigue and Dyspnea

By Sriram Yennurajalingam, MD1, Eduardo Bruera, MD1 | May 15, 2013
1Department of Palliative Care and Rehabilitation Medicine, M. D. Anderson Cancer Center

  • TABLE OF CONTENTS
  • Fatigue
  • Dyspnea
  • Suggested Reading

Suggested Reading

On Fatigue

Bruera E, Driver L, Barnes EA, et al: Patient-controlled methylphenidate(Drug information on methylphenidate) for the management of fatigue in patients with advanced cancer: A preliminary report. J Clin Oncol 21:4439–4443, 2003.

Bruera E, El Osta B, Valero V, et al: Donepezil(Drug information on donepezil) for cancer fatigue: A double-blind, randomized, placebo-controlled trial. J Clin Oncol 25:3475–3481, 2007.

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Bruera E, Strasser F, Shen L, et al: The effect of donezepil on sedation and other symptoms in patients receiving opioids for cancer pain: A pilot study. J Pain Symptom Manage 26:1049–1054, 2003.

Cleary J: The reversible causes of asthenia in cancer patients, in Portenoy R, Bruera E (eds): Topics in Palliative Care, vol 2, pp 183–202. New York: Oxford University Press, 1998.

Dimeo F, Stieglitz R, Novelli-Fischer U, et al: Effects of physical activity on the fatigue and psychological status of cancer patients during chemotherapy. Cancer 85:2273–2277, 1999.

Hann DM, Garovoy N, Finkelstein B, et al: Fatigue and quality of life in breast cancer patients undergoing autologous stem-cell transplantation: A longitudinal comparative study. J Pain Symptom Manage 17:311–319, 1999.

Henoch I, Bergman B, Gustafsson M, et al: Dyspnea experience in patients with lung cancer in palliative care. Eur J Oncol Nurs 12:86–96, 2007.

Howell SJ, Radford JA, Adams JE, et al: Randomized placebo-controlled trial of testosterone replacement in men with mild Leydig cell insufficiency following cytotoxic chemotherapy. Clin Endocrinol 55:315–324, 2001.

Munch TN, Zhang T, Willey J, et al: The association between anemia and fatigue in patients with advanced cancer receiving palliative care. J Palliat Med 8:1144–1149, 2005.

Neuenschwander H, Bruera E: Pathophysiology of cancer asthenia, in Portenoy R, Bruera E (eds): Topics in Palliative Care, vol 2, pp 171–181. New York: Oxford University Press, 1998.

Sadler IJ, Jacobsen PB, Booth-Jones M, et al: Preliminary evaluation of a clinical syndrome approach to assessing cancer-related fatigue. J Pain Symptom Manage 23:406–416, 2002.

Segal RJ, Reid Rd, Courneya KS, et al: Randomized controlled trial of resistance or aerobic exercise in men receiving radiation therapy for prostate cancer. J Clin Oncol 27:344-351, 2009. 

Seidenfeld J, Piper M, Flamm C, et al: Epoetin treatment of anemia associated with cancer therapy: A systematic review and meta-analysis of controlled clinical trials. J Natl Cancer Inst 93:1204–1214, 2001.

On Dyspnea

Allard P, Lamontagne C, Bernard P, et al: How effective are supplementary doses of opioids for dyspnea in terminally ill cancer patients? A randomized continuous sequential clinical trial. J Pain Symptom Manage 17:256–265, 1999.

Bausewein C, Booth S, Gysels M, et al: Non-pharmacological interventions for breathlessness in advanced stages of malignant and non-malignant diseases. Cochrane Database Syst Rev (2):CD005623, 2008.

Bruera E, Schmitz B, Pither J, et al: The frequency and correlates of dyspnea in patients with advanced cancer. J Pain Symptom Manage 19:357–362, 2000.

Currow DC, Agar M, Smith J, et al: Does palliative home oxygen improve dyspnoea? A consecutive cohort study. Palliat Med 23:309–316, 2009.

Currow DC, Smith J, Davidson PM, et al: Do the trajectories of dyspnea differ in prevalence and intensity by diagnosis at the end of life? A consecutive cohort study. J Pain Symptom Manage 39:680–690, 2010.

Mancini I, Body JJ: Assessment of dyspnea in advanced cancer patients. Support Care Cancer 7:229–232, 1999.

Reddy SK, Parsons HA, Elsayem A, et al: Characteristics and correlates of dyspnea in patients with advanced cancer. J Palliat Med 12:29–36, 2009.

Ripamonti C, Fulfaro F, Bruera E: Dyspnea in patients with advanced cancer: Incidence, causes, and treatments. Cancer Treat Rev 42:60–80, 1998.

Simon ST, Higginson IJ, Booth S, et al: Benzodiazepines for the relief of breathlessness in advanced malignant and non-malignant diseases in adults. Cochrane Database Syst Rev (1):CD007354, 2010.

Xue D, Abernethy A: Management of dyspnea in advanced lung cancer: Recent data and emerging concepts. Curr Opin Support Palliat Care 4:85–91, 2010.  

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Cancer Management: Palliative and supportive care

Pain Management

Management of Nausea and Vomiting

Fatigue and Dyspnea

Anorexia and Cachexia

Long-Term Central Venous Access






 
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