Daniel W. Bowles, Krishna Reddy, et al; ONCOLOGY Vol. 25 No. 11
Management of head and neck squamous cell carcinoma in the primary and relapsed setting requires the coordinated efforts of head and neck surgeons, radiation oncology, and medical oncology in order to maximize clinical care. Multidisciplinary efforts must be strengthened and new research performed to improve the otherwise poor prognosis for patients with locally recurrent HNSCC.
• Malignant Angiomyolipoma: a Rare Entity With Unusual Biology
Elaine T. Lam et al; ONCOLOGY Vol. 25 No. 9
The patient is a 43-year-old man who was initially evaluated at an outside institution for unexplained anemia and who was found to have a large right kidney mass. He underwent a radical nephrectomy for a 19-cm large-cell, poorly differentiated neoplasm.
• An Approach to the Management of Rare Tumors
• Pleomorphic LCIS: A Divergent Entity With Emerging Significance
Nicole Kounalakis, Jennifer Diamond, et al; ONCOLOGY Vol. 25 No. 4
A 40-year-old premenopausal woman with a new diagnosis of invasive lobular carcinoma occurring in a background of lobular carcinoma in situ presents to a multidisciplinary second opinion clinic.
• The Impact of Lobular Histology on Breast Cancer Treatment
A Young Woman With Multiple Kidney Lesions
Thomas W. Flaig, MD1,
Kimi L. Kondo, DO2,
Francisco G. La Rosa, MD3,
Brian Kavanagh, MD4,
E. David Crawford, MD5
, March 22, 2010
The patient is a 26-year-old woman with a complex oncologic history. At 1 year of age, she was diagnosed with a stage III abdominal neuroblastoma, which was treated with surgery and combination chemotherapy. At age 9, she had a recurrence of neuroblastoma in the left axilla. She was in her usual state of good health until 18 months ago, when she presented with hematuria and was found to have a right-sided kidney mass.
Recurrent Urothelial Carcinoma With Pulmonary Metastasis
Vassilis J. Siomos, MD1, Francisco G. La Rosa, MD2, Thomas W. Flaig, MD3, Kimi L. Kondo, DO4, J.D. Mitchell, MD5, Shandra Wilson, MD6, Al B. Barqawi, MD, FRCS7
, December 17, 2009
A 56-year-old woman was referred to our institution for a left nephroureterectomy after the diagnoses of a nonfunctioning left kidney and noninvasive papillary urothelial carcinoma of the distal left ureter (Ta grade 1). CT scan of the abdomen and pelvis demonstrated a large bladder tumor with pan-urothelial extension.
Response to Antiangiogenesis Therapy in a Patient With Advanced Adult-Type Testicular Granulosa Cell Tumor
Michael R. Harrison, MD1, Wei Huang, MD2, Glenn Liu, MD3, Jason Gee, MD4
, August 18, 2009
We have presented the first case of a patient with metastatic ATGCT with peritoneal carcinomatosis, who responded to treatment with a VEGFR tyrosine kinase inhibitor. Because of the relative paucity of such cases in the literature, no clear treatment strategy exists. For patients with metastatic ATGCT, enrollment in clinical trials testing novel therapies, including angiogenesis inhibitors, is a reasonable option.
Early-Stage BRCA2-Linked Breast Cancer Diagnosed in the First Trimester of Pregnancy Associated With a Hypercoagulable State
Jennifer R. Diamond, MD1, Christina A. Finlayson, MD2, Christiane Thienelt, MD3, Peter Kabos, MD4, Laura Hardesty, MD5, Linda Barbour, MD, MSPH6, Catherine E. Klein, MD7, Rachel Rabinovitch, MD8, Anthony Elias, MD9, Virginia F. Borges, MD, MMSC10
, August 17, 2009
This feature examines the case of a patient with newly diagnosed breast cancer in the setting of a first-trimester pregnancy presenting to our multidisciplinary breast cancer clinic.
Supraclavicular Extraskeletal Myxoid Chondrosarcoma Presenting With a Sensorimotor Polyneuropathy Associated With Anti-Hu Antibodies
Andres Deik, MD1, Efat Azizi, MD2, Ilan Shapira, MD3,
Irene R. Boniece, MD4
, July 16, 2009
This case shows the importance of searching for antineural antibodies in oncologic patients with new neurologic deficits, and of having a judicious workup for occult malignancies in patients with known antineural antibodies.
• Unraveling the Mystery of a Supraclavicular Mass
Unexpected N2 Lymph Node Involvement Found During Surgery for Early-Stage NSCLC
Scott A. Kono, DO1, Michael Weyant, MD2, Wilbur Franklin, MD3, Laurie E. Gaspar, MD4, D. Ross Camidge, MD, PhD5
, April 30, 2009
During investigation of an episode of self-limiting abdominal pain, a 63-year-old Caucasian female never-smoker was found to have an asymptomatic right lower lobe pulmonary mass.
A Patient With Metastatic Melanoma of the Small Bowel
John Park, BA1, Matthew B. Ostrowitz, MD1, Mark S. Cohen, MD1, Mazin Al-Kasspooles, MD, FACS1
, December 31, 2008
A review of the current literature describing this rare occurrence, metastatic melanoma of the small bowel, is included to compare with our patient's presentation, diagnosis, and management.
• Aggressive Surgical Therapy for Metastatic Disease Is Appropriate
The Absent-Minded Professor: An Unusual Complication of Melanoma
Ragini Kudchadkar, MD1, Rene Gonzalez, MD2, William Robinson, MD, PhD3, Maude Becker, RN4, Krista Treichel, RN4, Alan Kimura, MD5, Karl Lewis, MD6
, December 1, 2008
The patient is a geology professor who was evaluated in our multidisciplinary cutaneous oncology clinic for a new diagnosis of malignant melanoma with subsequent development of metastatic disease and melanoma-associated retinopathy.
Management of a Patient With Borderline Resectable Pancreatic Cancer
Anand P. Shah, MD1, Jonathan B. Strauss, MD1, William T. Leslie, MD2, Amar Shah, MD3, Brett Mahon, MD4, Ross A. Abrams, MD1
, November 30, 2008
In this case report, we discuss the presentation, workup, and therapeutic management of a 40-year-old man who presented with borderline resectable, periampullary pancreatic cancer and underwent a margin-negative resection following neoadjuvant chemoradiotherapy.
• Novel Approaches to ‘Borderline Resectable’ Pancreatic Tumors
A Perimenopausal Woman With a Small, ER/HER2–Positive, Node-Negative Breast Cancer
Gabriel Brooks, MD
Department of Medicine
Virginia Borges, MD
Division of Medical Oncology
Meenakshi Singh, MD
Department of Pathology
Rachel Rabinovitch, MD
Department of Radiation Oncology
Christina Finlayson, MD
Department of Surgery
Director, Breast Center
Anthony Elias, MD
Division of Medical Oncology
Director, Breast Cancer Research Program
University of Colorado School of Medicine
, October 1, 2008
This installment of Second Opinion examines the case of a patient with a new diagnosis of breast cancer presenting to our multidisciplinary breast cancer second opinion clinic.
Granulocytic Sarcoma in a Patient With Myelodysplastic Syndrome
Chirag Shah, MD1,
Srivalli Gopaluni, MD1,
Juhi Husain, MD1,
Arun Rajan, MD1,
Hemangini Shah, Do1
, July 1, 2008
Our case illustrates the fact that MDS-associated GS can be treated palliatively with radiation and hypomethylating agents in an appropriate setting. With the growing geriatric patient population, effective treatment options are needed in this disease.
Paraganglioma: A Potentially Challenging Tumor
Mark Trombetta, MD1,
Jan Silverman, MD2,
Athanasios Colonias, MD1,
Vincent Lee, MD1,
Alok Mohanty, MD2,
David Parda, MD1
, March 1, 2008
The development of metastatic disease in patients with paraganglioma is an unusual and challenging event. This case report and review describes the specific features of this disease and the multiple therapeutic options.
• An Uncommon Manifestation of an Uncommon Disease
Intracystic Papillary Carcinoma of the Breast: Differential Diagnosis and Management
Kimberly C. Mugler, MD1, Carrie Marshall, MD2, Lara Hardesty, MD3, Christina Finlayson, MD4, Meenakshi Singh, MD5
, May 31, 2007
We present a case of intracystic papillary carcinoma of the breast associated with low-grade ductal carcinoma in situ in a young woman. This is a distinct subtype of intraductal carcinoma that typically presents in postmenopausal women with a favorable prognosis.
A Woman With Primary Breast Cancer and a Solitary Sternal Metastasis
Alexander Menter, MD1, Alexander Urquhart, MD2, Virginia Borges, MD3, Rachel Rabinovitch, MD4, Meenakshi Singh, MD5, William Robinson, MD6, Paul Seligman, MD7, Christina Finlayson, MD8, Anthony Elias, MD9
, August 1, 2006
The patient presented to her primary care physician 3 months prior with an inverted left nipple and a palpable lump that was highly suggestive of neoplasm on mammogram. An ultrasound-guided core biopsy revealed an infiltrating solid-type ductal carcinoma in situ.
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FROM PHYSICIANS PRACTICE
Five Steps to Improving Patient Access Judy Capko,
May 21, 2013
Patient access is getting increased attention through reform initiatives. Here are five steps you can take to make sure patients get appropriate access to care in your office.