Tumor stroma is an important modulator of cancer cell behavior. In primary colorectal cancer, stromal composition may greatly influence the risk for liver metastases. After analyzing colon cancer tissue samples, researchers in Sweden pinpointed two types of growth patterns in colorectal liver metastases that can take the disease down dramatically different paths in terms of recurrence, mortality, and survival.
RESULT:Liver-metastatic Potential of Colorectal Cancer Is Related to the Stromal Composition of the Tumour
Anticancer Research | Dec 6, 2012 (FREE FULL TEXT)
The resection of a prostate or bladder tumor often leads to the formation of eosinophilia, commonly known as prostatitis or cystitis, respectively. But Japanese pathologists were surprised to find instances of dangerously high levels of white blood cells in metastatic liver cancer after cholecystectomy. They explain why clinicians need to keep an eye out for what they call “peculiar phenomena of eosinophil accumulation...after cholecystectomy.”
RESULT: Marked infiltration of eosinophils in necrotizing granulomas in the resected hepatic bed after cholecystectomy resulting from gallbladder cancer and metastatic liver cancer is associated with peculiar peripheral eosinophilia
Medical Molecular Morphology (PubMed) | Dec 01, 2012 (Free abstract. Full text $39.95)
Liver Metastasis Offers Clues on Disease Progress and Outcomes
December 19, 2012
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