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Oncology NEWS International. Vol. 16 No. 11
Industry Watch 

Phase II trials planned for oral methylnaltrexone for chronic pain

November 1, 2007

COLLEGEVILLE, Pennsylvania—Wyeth Pharmaceuticals and Progenics plan to initiate two 4-week phase II clinical trials to evaluate daily dosing of oral methylnaltrexone in patients with chronic, nonmalignant pain who are experiencing opioid-induced constipation (OIC). An NDA for the subcutaneous formulation has been filed with FDA for the treatment of OIC in the end-of-life setting.

 

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