 REVIEW ARTICLE
Mark Messina et al; ONCOLOGY Vol. 27 No. 5
Recently published research questions the need for the advised restriction against the use of soyfoods by women with a history of breast cancer. • Soyfood Consumption in Breast Cancer Survivors: Don't Overstate the Facts!
• A Fitting Prescription for All: Whole Soyfoods as Part of a Varied Plant-Based Diet REVIEW ARTICLE
Rajan T. Gupta et al; ONCOLOGY Vol. 27 No. 4
Our aims in this article are to describe the various imaging sequences that comprise the multiparametric MRI exam, as well as to review current literature on the strengths/weaknesses of these sequences. • The State of Prostate MRI in 2013: Into the Breach
• Multiparametric MRI: Standardizations Needed REVIEW ARTICLE
Amelia B. Zelnak, Ruth M. O'Regan; ONCOLOGY Vol. 27 No. 3
Additional insight into the biology of ER-positive breast cancers, particularly the higher risk luminal B cancers, could aid in identifying potential targets and new, effective therapies. • Omics as Useful Tools in Clinical Practice: Are We There Yet?
• The Evolving Role of Multi-Gene Tests in Breast Cancer Management CONFERENCE REPORT
Cancer Network brings exclusive coverage of the annual meeting of the American Association for Cancer Research (AACR), held April 6-10, 2013 at the Walter E. Washington Convention Center in Washington, DC. This meeting brings together the best and latest findings in all major areas of cancer research. • T-DM1 Most Effective in Breast Cancer Patients With High HER2 Expression
• Triple-Negative Breast Cancer—Utilizing Biomarkers for Better Therapeutic Strategies  REVIEW ARTICLE
Matvey Tsivian, Michael R. Abern, Thomas J. Polascik; ONCOLOGY Vol. 27 No. 1
In this review we focus on the recent evolution of the concept of focal therapy and the potential applications of this management approach within an array of options currently available for patients with localized prostate cancer. • Focal Therapy: A New Active Surveillance Tool?
• Focal Therapy of Prostate Cancer—The Challenge
Genomic Subtypes in Choosing Adjuvant Therapy for Breast Cancer
Amelia B. Zelnak, MD, MSc1, Ruth M. O'Regan, MD1
, March 11, 2013
Additional insight into the biology of ER-positive breast cancers, particularly the higher risk luminal B cancers, could aid in identifying potential targets and new, effective therapies. And though the majority of triple-negative breast cancers are the “basal-like” subtype, significant proportions are in other subtypes.
• Omics as Useful
Tools in Clinical Practice: Are We There Yet?
• The Evolving Role
of Multi-Gene Tests in Breast Cancer Management
Diffuse Large B-Cell Non-Hodgkin Lymphoma in the Very Elderly: Challenges and Solutions
Shadi Latta, MD1,
Peter H. Cygan, MD1,
Walter Fried, MD1,
Chadi Nabhan, MD, FACP1
, February 15, 2013
In this review, we critically analyze clinical trials that were specifically designed for the very elderly, and we discuss the challenges encountered by investigators who are conducting studies in this patient population. We conclude by proposing an algorithm to help clinicians determine the optimal therapeutic strategy for treatment of DLBCL in very elderly patients.
• When Can R-CHOP Not Be Used in an Elderly Patient?
• The Case for Refining Our Clinical Trials
• DLBCL in the Elderly: Leaving Our Old Way(s) Behind?
Intraoperative Radiotherapy for Breast Cancer: Its Perceived Simplicity
Robert B. Ash, MD1,
Venita L. Williams, MD1,
Lawrence D. Wagman, MD1,
Afshin Forouzannia, MD1
, February 15, 2013
With many centers seeking to adopt IORT, there are licensing, proctoring, staffing, technical support, and reimbursement issues that need to be considered. We have reviewed the current international experience and describe one community cancer center’s experience with initiating an IORT breast cancer program.
• On the Road to Intraoperative Radiotherapy: More 'Proceed With Caution' Signs
• Intraoperative Radiotherapy for Breast Cancer: Deceptively Simple?
"OMG, How Long Is This Going to Take?"
Jimmie Holland, MD1
, February 15, 2013
It is hard to realize that an elderly patient's visit to you is likely the only trip outside his or her apartment for the week and the only contact with someone other than family or an aide. Doctor visits sometimes become the elderly's primary contact with the larger world.
Ethical Challenges in Oncology, Explored Through a Series of Vignettes
Laura Tenner, MD1,2,3,
Paul R. Helft, MD1,2,3
, February 15, 2013
In this article, we have chosen to focus on three ethical challenges that we believe practicing oncologists might commonly encounter with their patients. The ethical dilemmas are presented in a case-based approach in the hope of better joining the ethical theory to clinical practice.
• Rationing Healthcare: Who's Responsible?
• The Need to Individualize Advanced Cancer Care
Financial Toxicity, Part I: A New Name for a Growing Problem
S. Yousuf Zafar, MD, MHS1, Amy P. Abernethy, MD1
, February 15, 2013
Costs of care continue to rise; new cancer drugs are more expensive than ever before, and more patients are being treated with these drugs. While patients and claims datasets consistently report an association between financial burden and quality of care, the impact on traditional disease-related outcomes—survival, for example—have not been assessed.
Clinical Trials Need to Control for the Influence of Palliative Care on Outcomes
Nora Janjan, MD, MPSA, MBA1
, January 15, 2013
To insure standardization of all aspects of care during the conduct of a clinical trial, clinical trials should include guideline-based criteria for the management of all symptoms of cancer and its treatment, and failure to adhere to any of the standards for symptom management during the conduct of the trial should result in an equal level of protocol violation.
Palliative Care Always
Kavitha Ramchandran, MD1,2,
Jamie H. Von Roenn, MD3,4
, January 15, 2013
In this article, we present or review the evidence for providing palliative care concurrently with oncologic care, guideline-based recommendations for screening and incorporation of palliative care, and a case-based discussion to demonstrate palliative care across the continuum of cancer care.
• Early Palliative Care: Moving From ‘Why’ to ‘How’
• Integrating Palliative Care Into Oncology Care: Confronting the Barriers
50 Shades of Pink—And Why It Helps to Know the Difference
Rebecca Bechhold, MD1
, May 17, 2013
Buy toxic chemicals and support breast cancer research! Not lying—just saw an ad on TV for weed killer and it had a pink ribbon logo on its packaging indicating, “A portion of every sale goes to support breast cancer research and awareness.” We have plenty of weed killer and a perfect lawn at our house, so I am no critic of the product. But have you noticed the pink ribbon logo on virtually every conceivable item or service?
I Can’t Talk to You With a Gun in My Face
Rebecca Bechhold, MD1
, May 3, 2013
How many times have you been killed for being the messenger with the bad news? You can often tell who is going to be angry when the CT scan shows recurrent disease. It is one of many things that are so stressful about being an oncologist. Let’s be honest; over the course of our career, we give a lot of bad news.
“This Is My Last Day on Earth”
Craig R. Hildreth, MD
, May 2, 2013
To my oncologist: You certainly were pleasant and compassionate. You also tended to minimize the gravity of the situation when my disease progressed. I know you’re not psychic, but when things are going badly, don’t be afraid to tell me you’re worried.
Conflicts of Interest in Medicine: What About Ties to Payers?
Frederic W. Grannis Jr., MD1
, April 5, 2013
Recently, the US government released new “Sunshine” standards requiring more rigorous disclosure of potential financial conflicts of interest in medicine. Such new standards are driven by revelations of misdeeds on the part of pharmaceutical and device manufacturers.
“How Do I Say This Nicely? Your Oncologist Wasn't Following Guidelines”
Rebecca Bechhold, MD1
, March 26, 2013
When you start seeing a patient for the first time who has been treated elsewhere and the previous oncologist has not followed standard protocol, how do you present this new way of doing things without alienating the patient or sounding critical of the previous doctor?
ONS: Infection Risk, Prevention, and Management
April 29, 2013
In this interview, Laura Zitella will be discussing challenges and considerations for management and prevention of infection in the oncology setting—in both patients with solid tumors and those with hematologic malignancies.
ONS: Nurse-Physician PACT Yields Sharp Decrease in Codes
April 29, 2013
A team of nurses and physicians from Huntsman Cancer Institute successfully implemented key changes in their Patient Acute Change Team that increased nurse involvement and reduced the number of codes by 90% in the outpatient setting since they were put in place 2 years ago.
ONS: Safe Handling of Chemotherapy
April 29, 2013
Oncology nurses from a community hospital in Cincinnati, Ohio implemented a two-pronged process for the safe handling of chemotherapy, improving nurses’ satisfaction and comfort levels regarding chemotherapy safety.
ONS: Genetics and Genomics Matters
April 25, 2013
This interview covers standards for healthcare provider competency in offering comprehensive genetic services, and highlights genetics/genomics resources for nurses.
Current Challenges in Metastatic Breast Cancer: Patient Management and Treatment Strategies Interactive Case Challenge Series  This series of case presentations (five individual cases) will provide oncologists and other healthcare professionals with strategies for evaluating evidence-based data on the latest treatments in metastatic breast cancer (MBC) and the application of that data into the development of individualized approaches to care, including overcoming resistance, in order to optimize management and outcomes for patients.
Go to Activity
CancerNetwork.com offers a variety of Continuing Medical Education (CME) programs based on ONCOLOGY review articles, supplements to ONCOLOGY, textbooks, roundtable discussions, e-learning programs, and webcasts.  These interactive CME activities are offered to physicians and other healthcare professionals without charge by CME.
CME LLC is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
See a list of more Oncology CME activities.
Diagnostic Champions’ Challenge on Cancer Network: Designed to test the knowledge and medical diagnostic skills of physicians and other healthcare professionals, Cancer Network's Diagnostic Champions' Challenge was created to educate and entertain. Test your skills by playing… Read More»
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Five Steps to Improving Patient Access Judy Capko, May 21, 2013 Patient access is getting increased attention through reform initiatives. Here are five steps you can take to make sure patients get appropriate access to care in your office.
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In this review we focus on the recent evolution of the concept of focal therapy and the potential applications of this management approach within an array of options currently available for patients with localized prostate cancer.
A 52-year-old man presented with an erythematous lesion in the axilla of unknown duration. Surgical excision was performed. What is your diagnosis?
We speak with two experts to discuss breast cancer risk, genetics, and prevention options available to women at high risk of developing breast and ovarian cancer.
