A 38-year-old man presents with abdominal pain and general malaise. He has no previous history of any particular disease, but recently lost some weight and feels tired. At the physical exam there is some lymphadenopathy and the spleen is enlarged. A splenectomy is performed.
C. Inflammatory Pseudotumor (IPT)
IPT is an unusual condition that may affect several organ systems, mainly the hematopoietic system including lymph nodes and the spleen. The lesion is characterized by the presence illustrated here of a spindle cell proliferation (fibroblastic) and presence of inflammatory cells, mainly plasma cells. IPT may be an autoimmune process. Although IPT is not a malignant process, it may be difficult to control when many organ systems are involved. This lesion is also known in other anatomical regions as a myofibroblastic tumor.