The Correct Answer for Question 1 is D: CML
The Correct Answer for Question 2 is A: t(9;22) (q34;q11)
A majority of CML patients have the BCR/ABL gene. This gene is the result of a 9;22 translocation (aka Philadelphia chromosome), part of the BCR region from chromosome 22 fuses with the ABL gene on chromosome 9. This abnormal gene generates tyrosine kinase that promotes increased cell growth.
Branford S, Hughes TP Mutational analysis in chronic myeloid leukemia: when and what to do? Curr Opin Hematol. 2011 Mar;18(2):111-6. PMID: 21245758