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TEST YOUR IMAGE IQ

Carcinoma of the Lung

By Robert D. Cardiff, MD, PhD | June 17, 2011

Professor of Pathology, Emeritus, Center for Comparative Medicine, University of California, Davis

Answer 1: A (Non–small-cell lung cancer)

Answer 2: B (Desmosomes)

Comment: Lung cancers are now classified as: non–small-cell lung cancer (which includes squamous cell carcinoma and adenocarcinoma) or small-cell carcinoma with a miscellaneous category (including pleomorphic, carcinoid, salivary gland, and unclassified). Within these morphological types, numerous genetic alterations have been found. The literature has numerous studies implicating genetic and epigenetic changes that lead to tumorigenesis as well as implications for prognosis and treatment.

This Image IQ has been provided by the Center for Genomic Pathology

Reference:
Sy SM, Wong N, Lee TW, et al. Distinct patterns of genetic alterations in adenocarcinoma and squamous cell carcinoma of the lung. Eur J Cancer. 2004 May;40:1082–1094. PubMed PMID:15093586.

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TOPIC INDEX

Cancer Types
Breast Breast (HER2+) Breast (Triple-Negative) CML Colorectal Gastrointestinal GIST Genitourinary Gynecologic Head & Neck	Hematology Kidney (Renal Cell) Leukemia Lung Lymphoma Melanoma Multiple Myeloma Ovarian Prostate Sarcoma
Supportive Care	More Topics
Bone Metastases End-of-Life Care Palliative Care	Ethics in Oncology Practice Management Practice & Policy

All Topics