D. Acinic-cell adenocarcinoma
Acinic-cell adenocarcinoma is an epithelial tumor more commonly occurring in the parotid gland. However, the tumor may also occur in minor salivary glands. The tumor does not appear to have predilection for either gender. It is more common in adults over 20 years of age.
The tumor may have variable histological appearance and immunohistochemical stains have limited valued in the diagnosis.
The tumor can metastasize to lymph nodes or other anatomical areas. The treatment of choice is complete surgical resection (parotidectomy) and if accomplished the prognosis appears to be good. However, when complete surgical resection is not possible or when there is metastatic disease, adjuvant treatment in the form of radiation therapy may be needed.
1. Stennert E, Kisner D, Jungehuelsing M, et al. High incidence of lymph node metastasis in major salivary gland cancer. Arch Otolaryngol Head Neck Surg. 2003;129:720-723. PubMed