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Children with acute lymphoblastic leukemia gain little by participating in clinical trials
Parents and their children need to understand that advancing science does not always go hand-in-hand with a direct benefit to the patients. More »
Blood count test may predict prognosis in leukemia
A multi-institutional group of researchers have zeroed in on a more accurate way to decipher treatment outcomes in young leukemia patients using information from a simple complete blood count test. More »
FDA Approves Rituximab for Chronic Lymphocytic Leukemia
The US Food and Drug Administration recently approved rituximab (Rituxan) to treat certain patients with chronic lymphocytic leukemia (CLL). More »
Chronic myeloid leukemia
Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder resulting from the neoplastic transformation of the primitive hematopoietic stem cell. The disease is monoclonal in origin, affecting myeloid, monocytic, erythroid, megakaryocytic, B-cell, and, sometimes, T-cell lineages. Bone marrow stromal cells are not involved. More »
Chronic lymphocytic leukemia
Chronic lymphocytic leukemia (CLL) is a clonal malignancy that results from expansion of the mature lymphocyte compartment. This expansion is a consequence of prolonged cell survival, despite a varied cell. The affected lymphocytes are of B-cell lineage in 95% of cases, and the remaining cases involve T lymphocytes, representing a distinct disorder. More »
Younger acute myelogenous leukemia patients respond favorably to anthracycline dose intensification
Induction therapy with higher daily doses of daunorubicin improved complete response and boosted overall survival in younger patients with acute myelogenous leukemia, according to results of the phase III ECOG E1900 trial. More »
Acute Lymphoblastic Leukemia Presenting as Soft Tissue Mass
For 3 months, a 9-year-old boy had swelling of the left upper arm. An MRI scan obtained at another facility 1 week after onset showed extensive edema of the soft tissue at the midhumeral level. Laboratory results, including complete blood cell (CBC) count and Lyme titer, were normal.
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Bendamustine plus rituximab offers new standard of care for treatment of NHL and indolent lymphoma
There was good news at ASH 2009 on promising treatments for indolent lymphoma and aggressive non-Hodgkin's lymphoma. More »
Voreloxin Gets Orphan Drug Status for Acute Myeloid Leukemia
Advances in Genetics and Treatment Protocols Lead to Significant Progress in Leukemia and Myeloproliferative Disorders
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