The incidence of pediatric Hodgkin lymphoma (HL) has been on the upswing in many countries over the last few decades. Researchers in Sweden took a closer look at any possible perinatal risk factors for the disease in a cohort of more than 3 million people. The two intriguing key elements strongly associated with a higher risk for HL from ages 0 to 37, fetal growth rate and family history, suggest tantalizing links to growth factor pathways.
RESULT: Perinatal and Family Risk Factors for Hodgkin Lymphoma in Childhood Through Young Adulthood
American Journal of Epidemiology | Nov 21, 2012 (Free abstract. Full text $40)
From genetic sequencing in Burkitt lymphoma (abstract 12) to the expanding role of immunotherapy in HL (abstract 127), the presentations from the 2012 International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin's Lymphoma, held last month, offer the latest in cutting-edge research in this subspecialty. This year's abstracts also have real-world clinical news in the form of case studies, including one on a rectal polyp that turned out to be a rare case of pediatric follicular lymphoma (abstract 147).
RESULT: Abstracts of the Fourth International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin's Lymphoma
British Journal of Haematology (PubMed) | Nov 01, 2012 (FREE FULL TEXT)
A hematologically stable CML patient developed a solitary, exquisitely painful ulceration, 7 cm × 5 cm, located on the mid-medial foreleg. There was never any evidence of venous insufficiency. The patient denied the possibility of a spider bite. What is the likely cause of this lesion?
