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Lung Cancer

Using Immune Checkpoint Inhibitors in Lung Cancer

Immune checkpoint inhibitors have changed the treatment paradigm for patients with lung cancer, bringing about the most promising outcomes we have seen in a long time.

Lung Cancer

A delay in initiation of adjuvant chemotherapy following resection for non–small-cell lung cancer was not associated with any increase in mortality.

A database analysis shows significant shifts in treatment patterns for elderly patients diagnosed with advanced-stage non–small-cell lung cancer, along with a modest gain in survival since 2000.

In this interview we discuss the use of liquid biopsies in lung cancer, the pros and cons compared with tissue biopsies, and how they can be used to help make treatment decisions.

The PD-L1 inhibitor atezolizumab significantly improved overall survival compared with docetaxel across subgroups of patients with non–small-cell lung cancer.

Pembrolizumab was associated with clinically meaningful improvements in health-related quality of life compared with platinum-based chemotherapy in NSCLC patients.

Patients treated with first-line ceritinib had a 45% reduction in the risk for progression of advanced ALK-positive NSCLC compared with chemotherapy.

Second-line treatment with osimertinib resulted in significantly better progression-free survival compared with chemotherapy alone in patients with EGFR-T790M positive NSCLC, according to the results of the AURA3 trial.

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