ASA404 fails second late-stage lung cancer trial

By Shalmali Pal | December 23, 2010

Novartis and its partner Antisoma announced that an interim analysis of data from a late-stage trial showed that vadimezam (ASA404) was unlikely to provide any benefit as a second-line treatment for patients with non-small-cell lung cancer. As a result, Novartis indicated that it would halt development of the compound, which was designed to inhibit angiogenesis.

The ATTRACT-2 study enrolled patients with advanced NSCLC whose disease had progressed after first-line therapy. In ATTRACT-1, ASA404 failed to demonstrate a survival benefit in previously untreated patients with NSCLC when used in combination with chemotherapy.

by Bob Ellal | December 28, 2010 9:57 AM EST

Qigong helped me beat four bouts of "terminal"bone lymphoma in the early nineties. It's also helped me manage the pain--physical and emotional--wrought by the cancer in the years since. Qigong also is an excellent stress reducer; after consistent practice life's "slings and arrows" bounce off one like pebbles plinking off a breastplate. Clear 14 years and still practicing every day!

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ASA404 fails second late-stage lung cancer trial

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