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FDA Approves Ixazomib (Ninlaro) for Multiple Myeloma
The FDA approved the proteasome inhibitor ixazomib, in combination with lenalidomide and dexamethasone, to be used as a second-line treatment in multiple myeloma.
Daratumumab Granted FDA Approval for Treatment-Resistant Multiple Myeloma
On November 16, 2015, the US Food and Drug Administration (FDA) approved daratumumab (Darzalex) to treat patients with multiple myeloma who have received at least three prior treatments.
Myeloma-Related Kidney Failure Declined in Recent Years
The risk for end-stage renal disease that required renal replacement therapy due to multiple myeloma appears to have declined significantly between 2001 and 2010.
Carfilzomib/Pomalidomide Active in Relapsed, Refractory Myeloma
A novel regimen of carfilzomib, pomalidomide, and dexamethasone was highly active in a group of heavily pretreated patients with relapsed or refractory multiple myeloma.
Financial Burden of Multiple Myeloma High, Even Among Insured
Seventy percent of insured patients with multiple myeloma had treatment-related financial burden, including some with household incomes greater than $100,000 a year.
Ixazomib Gets Priority Review for Multiple Myeloma
The FDA recently granted priority review status to ixazomib (Takeda) for the treatment of relapsed or refractory multiple myeloma.
Agent Orange Exposure Linked to Myeloma Precursor Risk
Vietnam War veterans exposed to Agent Orange as part of Operation Ranch Hand were at double the risk for monoclonal gammopathy of undetermined significance, a precursor to multiple myeloma, according to results of a new study.
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