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Zoledronic Acid Delayed Symptomatic Progression of Myeloma
Zoledronic acid did not have any antitumor effect in asymptomatic multiple myeloma patients in relapse, but did delay symptomatic progression and bone disease.
HDAC Inhibitor Active in Myeloma Maintenance Setting
Treatment with lenalidomide and the HDAC inhibitor vorinostat may be effective as a maintenance therapy in multiple myeloma patients after autologous transplant.
Results From the Multiple Myeloma Trials
We discuss some of the anticipated multiple myeloma trials with Sagar Lonial, MD, ahead of the 2015 American Society of Clinical Oncology Annual Meeting.
ASCT Offers Survival Advantage in Elderly Multiple Myeloma Patients
Autologous stem cell transplant led to significantly longer overall survival than non-transplant strategies in a cohort of elderly patients with multiple myeloma.
Adding Elotuzumab Improved PFS in Relapsed Multiple Myeloma
The addition of elotuzumab to lenalidomide and dexamethasone improved progression-free survival and overall response rate in relapsed multiple myeloma patients.
ENDEAVOR: Carfilzomib Doubles PFS in Relapsed Myeloma
Treatment with carfilzomib and dexamethasone doubled the PFS in relapsed multiple myeloma patients compared with treatment with bortezomib and dexamethasone.
Prior Knowledge of MGUS Linked to Improved Multiple Myeloma Survival
Multiple myeloma patients had better overall survival if they had prior knowledge of having monoclonal gammopathy of undetermined significance.
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