SAN FRANCISCOThe rate of breast-conserving surgery with adjuvant radiation therapy increased at a North Carolina community hospital (Durham Regional) after Duke University Medical Center radiation oncologists opened an on-site clinic. The study results were presented at the 43rd Annual Meeting of the American Society for Therapeutic Radiology and Oncology (abstract 87).
During the period when the radiation oncology clinic was located 5 miles from the community hospital, the rate of breast-conserving therapy was only 28.7%, said lead investigator Carol Hahn, MD, associate professor of radiation oncology at Duke and chief of the Division of Radiation Oncology at Durham Regional. After the radiation oncology clinic moved into the hospital, the incidence of breast-conserving therapy shot up to 43.7%.
Previous studies have shown that the rate of breast-conserving therapy is influenced by several variables, including patient age, insurance coverage, and geographic location. Why do such nonmedical variables influence therapy for breast conservation, the preferred treatment for many women with early breast cancer? Dr. Hahn asked. "We had a change in practice setting that allowed us to gain some insight into this," she said.
The researchers examined the community hospital’s pathology database to compare treatment of 262 breast cancer patients during 1994-1995 when radiotherapy was provided at Duke and 304 breast cancer patients during 1997-1998 after the move to the community hospital. Multivariate analysis revealed that the incidence of breast-conserving therapy increased significantly (P < .001) after the clinic moved on-site.
The incidence of breast-conserving therapy for patients with ductal carcinoma in situ (DCIS) did not change during the study and was much higher during both periods than for women with invasive cancer.
Dr. Hahn reported that the incidence of breast-conserving therapy in patients with invasive disease increased from approximately 21% before the move to 44% afterwards.