BETHESDA, MarylandA National Cancer Institute (NCI) panel, which explored how to improve survival among leukemia, lymphoma, and myeloma patients and stem the soaring death rates for those with non-Hodgkin’s lymphoma and multiple myeloma, has recommended giving priority to 10 areas of research.
The group also called for the creation of a formal, NCI-supported system to be known as the Cancer Translational Research Allied Consortium (C-TRAC), to speed the discovery and development of new therapies for hematologic cancers."The ultimate goal of the C-TRAC will be to shorten drug development time from 5 to 10 years to 2 years through a novel alliance among academic, industry, government, and patients," the report said.
The panel attributed the current long-development time to many barriers that "ultimately are related to the absence of adequate infrastructure for the development of the therapeutics." The C-TRAC concept is not meant to replace the research infrastructure of the pharmaceutical industry, but to create a parallel system for the rapid translation of research findings, the report said.
The 80-page report is the result of a 10-month effort by the 34-member Leukemia, Lymphoma, and Myeloma Progress Review Group (PRG), which included experts from NCI and from academia, industry, and advocacy organizations.
Priority Research Areas
The 10 priority research areas identified by the review group are: