Combining an investigational agent called PD 0332991 with letrozole improved progression-free survival over letrozole alone in women with advanced estrogen receptor-positive breast cancer, according to a study presented at the San Antonio Breast Cancer Symposium this week.
Researchers have developed a relatively simple breath analysis testing volatile organic compounds that may one day be used as a way to screen for colorectal cancer.
Breast cancer patients 35 years and younger, even those with luminal-like disease, derive more benefit from neoadjuvant chemotherapy than do older patients, according to a German study presented at SABCS.
In the first chemoprevention trial with a non-FDA-approved, oral, small-molecule-targeted agent, enzastaurin did not meet a primary endpoint but showed reasonable tolerability and some success in subgroup analyses.
SABCS: Increasing Fulvestrant Dose in Advanced ER-Positive Breast Cancer Yields Better Survival, Similar Toxicity
Increasing the dose of fulvestrant from 250 mg to 500 mg yielded a longer median overall survival as well as a lower overall risk of death in women with locally advanced or metastatic estrogen receptor-positive breast cancer, according to results from the CONFIRM trial.
A large cohort study found that black women with early-stage invasive breast cancer were significantly less likely than white patients to undergo the less invasive axillary sentinel lymph node biopsy. Black women also had a higher rate of lymphedema, due largely to that difference in treatment modalities.
A new study shows two chemotherapy drugs prevalent in the clinic—gemcitabine and 5-fluorouracil—may influence the immune response in a way that facilitates tumor growth.
Patients who took tamoxifen as adjuvant therapy for ER-positive breast cancer for 10 years had both a reduced risk of recurrence and better overall survival compared to patients who stopped after 5 years, according to results of the ATLAS study presented at SABCS.
Obese lung cancer patients undergoing lobectomy spend more time in the operating room than patients with lower body mass index, according to a new study. BMI was not associated with 30-day mortality or increased length of hospital stay.
Giving patients at the end of life regular parenteral hydration of 1 L of saline per day did not improve symptoms associated with hydration, quality of life, or survival, according to a randomized, placebo controlled study.