A large cohort study shows that women on antiestrogen therapy have a lower risk of melanoma. In a study of 7360 women diagnosed with breast cancer between 1980 and 2005, 54% were given supplemental antiestrogen therapy. The rate of cutaneous melanoma was 60% higher for those women not taking antiestrogen supplements compared with the expected rate of melanoma incidence based on age and other factors.
Inherited mutations in the ataxia telangiectasia mutated (ATM) gene increase the odds of developing pancreatic cancer according to a new study. While there is predisposition for pancreatic cancer with up to 10% of cases occurring among families with a history of the disease, the genetic basis for this had not been previously discovered.
A new finding suggests that inhibiting the cytokine interleukin-17A, produced by inflammatory cells of the immune system, may be a novel approach in the treatment of lung tumors.
A study has identified a gene fusion from a never-smoker lung cancer patient that may act as a driver in a subset of lung cancer cases. The results suggest that the newly identified fusion is not that rare and that the mutation exists in primary lung adenocarcinomas.
A study published in the journal Cancer shows that breast cancer survivors can experience problems with specific mental abilities up to several years after treatment.
Researchers from Wellspring, a Canadian nonprofit organization that supports and educates people with cancer, together with a team of patient-support consultants, have developed a 1-day program that appears to have reduced emotional exhaustion and burnout in oncology nurses.
Epidemiologist Jack Cuzick, PhD, and colleagues, writing in the Journal of the National Cancer Institute in April, concluded that “tamoxifen-induced reductions in breast density can be used to identify women who will benefit the most from prophylactic treatment with this drug.”
A team of researchers from the University of Connecticut at Storrs and the National Cancer Institute, analyzing US national health data on more than 4,000 racially diverse adults aged 75 years and older, has concluded that despite “ambiguity of recommendations for this group,” cancer screening rates are high in this population.
Expert Panel Points Out Short-Comings of Study Comparing Partial Breast Brachytherapy to Whole-Breast Irradiation Presented at SABCS
The results of a study presented at the San Antonio Breast Cancer Symposium (SABCS) prompted enough controversy to warrant a statement from 3 major medical societies and an expert panel teleconference on December 14, 2011 to discuss the analysis of data presented by the MD Anderson Cancer Center physicians.
ASH: Two Immunochemotherapy Regimens With Rituximab for Newly Diagnosed Follicular Lymphoma Show Equally Good Results
Results of the phase III SWOG S0016 trial comparing 2 chemotherapy regimens for follicular lymphoma (FL), presented this week at ASH, show no statistically significant differences in either progression-free survival (PFS) or overall survival. Both regimens produced “excellent” results, according to the presenter.