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The Journal of Musculoskeletal Medicine. Vol. 28 No. 2

MUSCULOSKELETAL Citations
Concise summaries of recent journal articles chosen for clinical significance

 

Early rheumatologist evaluation of RA improves outcomes

January 26, 2011

van der Linden MP, le Cessie S, Raza K, et al, Leiden University Medical Center, Leiden, the Netherlands, and University of Birmingham, UK. Long-term impact of delay in assessment of patients with early arthritis. Arthritis Rheum. 2010;62:3537-3546.


For patients with rheumatoid arthritis (RA), a shorter time to assessment by a rheumatologist is associated with longer disease-modifying antirheumatic drug (DMARD)-free remission times and less joint destruction. However, patients with early arthritis who have a diagnosis of RA experience one of the longest delays and only one-third are assessed within the “window of opportunity.”

van der Linden and associates evaluated patient, general practitioner (GP), and rheumatologist delay in 1674 patients with early arthritis; 598 had RA. The latter patients were evaluated for the relationships among total delay, achievement of DMARD-free remission, and rate of joint destruction over 6 years.

Among patients with early arthritis, the average patient, GP, and rheumatologist delays were 2.4, 8.0, and 13.7 weeks, respectively. Among persons with RA, the delay was longest at 18 weeks; most (67%) of these patients were seen 12 weeks or longer after receiving the diagnosis, and they had a hazard ratio of 1.87 for failure to achieve DMARD-free remission. They also had 1.3 times more joint destruction over 6 years than persons seen before 12 weeks.

The authors noted that diminishing the delay in assessment by a rheumatologist will be crucial to further improvement in disease outcomes.

 

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This commentary refers to the following article

Tofacitinib Monotherapy Reduced RA Signs and Symptoms






 
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