The Society of Gynecologic Oncology (SGO) recently issued two new clinical practice statements recommending genetic testing for all women with endometrial and ovarian cancers, regardless of family history.
A new study found that high concentrations of vitamin C increased the effectiveness of chemotherapy in an ovarian cancer mouse model. A high-dose delivery of the vitamin also resulted in lesser toxicity from chemotherapy in cancer patients.
Don Dizon, MD, Brown University, discusses the paradigm shift in the treatment of endometrial cancer with the use of medical therapy, including chemotherapy with biologics, mTOR inhibitors combined with chemotherapy, and targeted therapies.
While personalized medicine is seen as a way to target an individual cancer patient’s tumors, using targeted agents, immunotherapy, and chemotoxic drugs, researchers are increasingly finding that not only do the cancers of individuals vary widely, but that tumors within a patient can also be quite different at the molecular level.