Topics:

Prostate Cancer

The Bifunctional Role of Steroid Hormones

This review examines the relevance of a translational framework for studying therapeutic androgens in prostate cancer.

Commentaries:
New Concepts Regarding Testosterone and Prostate Cancer: A Breath of Fresh Air
Friend or Foe: The Bifunctional Role of Steroid Hormones in Prostate Cancer

Prostate Cancer

Following studies that found no survival or mortality benefit, we discuss the utility of primary androgen deprivation therapy in localized prostate cancer.

The adoption of robot-assisted radical prostatectomy is on the rise in the United States, according to the results of a retrospective study.

Patients with limited life expectancies often undergo routine cancer screenings despite evidence that they are unlikely to benefit and may experience harm.

This article reviews the most recent advances in androgen receptor-directed therapies for castration-resistant prostate cancer, and new agents under development.

In the past 5 years we have taken at least 7 steps forward for men with prostate cancer—which hopefully will turn into “one giant leap” in our attempt to convert advanced prostate cancer into a chronic disease.

This is an exciting time for physicians who care for patients with advanced prostate cancer, and more importantly a time of heightened optimism for these men and their families.

It is now well established that castration-resistant disease can be effectively treated using newer androgen receptor-targeting agents such as abiraterone and enzalutamide.

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