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CURRENT ISSUE

October 2011  |  Volume 25 • Number 10



Counseling Women at High Risk of Ovarian or Endometrial Cancer
Sue Rimes, RN1, Amanda Brandt, MS1,2, Jacalyn Gano, RN1, Elizabeth Keeler, MD1, Karen Lu, MD1,2 , October 19, 2011

CME
Patient education and counseling are essential in women at increased risk for ovarian and endometrial cancer. Women must be educated regarding the signs, symptoms, and risks associated with these cancers.
•The Complexity of Hereditary Cancer Syndromes

Elder Spousal Grief in the Context of Cancer Caregiving
Deborah A. Boyle, RN, MSN, AOCNS®, FAAN1 , October 19, 2011

Dying from cancer is predominantly an elder experience. The person with major responsibility to provide care for the ill family member is often the patient’s spouse, who frequently is an older adult.

Coenzyme Q10
Glenn J. Lesser, MD, FACP1, Mara Z. Vitolins, DrPH, MPH, RD2 , October 19, 2011

Coenzyme Q10, or CoQ10, is a naturally occurring, lipid-soluble antioxidant and an essential electron carrier involved in the mitochondrial respiratory chain. In mitochondria, CoQ10 functions as a coenzyme that assists in the oxidative phosphorylation of nutrients, leading to production of cellular adenosine triphosphate (ATP), or energy.

Our 9/11 Cancer Nursing Connection
Deborah A. Boyle, RN, MSN, AOCNS®, FAAN , October 18, 2011

Nearly 3,000 people died in the 9/11 tragedy 10 years ago. Yet I cannot help but put this fact into the context of one of the most challenging concerns in the field of public health today: cancer.

Vemurafenib, a BRAF Inhibitor for Patients With Unresectable or Metastatic Melanoma and V600E-Mutated BRAF Protein
Gail M. Wilkes, MS, APRN-BC, AOCN , October 18, 2011

Vemurafenib is a protein kinase inhibitor that blocks the mutated gene protein BRAFV600E so that the cascade of messages that drive cell division and prevent apoptosis is stopped, resulting in tumor shrinkage.

News of Note
October 18, 2011

News of note from the current literature.

HE4 Biomarker Test Is Approved for Use in Risk of Ovarian Malignancy Algorithm (ROMA)
October 18, 2011

In September 2011, the US Food and Drug Administration (FDA) approved marketing of the HE4 Test (Fujirebio Diagnostics, Malvern, Pennsylvania) along with the CA-125 test in the Risk of Ovarian Malignancy Algorithm, called ROMA, to determine the likelihood of finding malignancy at surgery in premenopausal or postmenopausal women presenting with an ovarian adnexal mass.

October Is National Breast Cancer Awareness Month
October 18, 2011

The National Breast Cancer Awareness Month (NBCAM) organization, which began its campaign in 1984, is a partnership of more than a dozen national professional medical associations, public service organizations, and government agencies that work together year-round to promote awareness of breast cancer, share up-to-date information about the disease, and provide greater access to screening services.

EMCC: AZURE Subgroup Analysis Shows Adjuvant Therapy With Zoledronic Acid May Benefit Breast Cancer Patients Postmenopausal > 5 Years
Anne Landry , September 29, 2011

Results of the AZURE trial revealed small improvements in disease-free and overall survival when zoledronic acid was used in addition to adjuvant therapy in a subgroup of early-stage breast cancer patients who had been postmenopausal for more than 5 years.