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Three SNPs Associated With Overall Survival in Pediatric Ewing Sarcoma
Three single-nucleotide polymorphisms were identified that are significantly associated with OS in two separate cohorts of pediatric Ewing sarcoma patients.
Anlotinib Offers Efficacy Across Subtypes of Soft-Tissue Sarcoma
A phase II trial showed that the tyrosine kinase inhibitor anlotinib has promising efficacy across a variety of subtypes of advanced refractory soft-tissue sarcoma.
Novel Drug Combination Shows Activity in Angiosarcoma
A combination of the endoglin antibody TRC105 and pazopanib shows promising activity in patients with advanced soft-tissue sarcoma, particularly angiosarcoma.
Quality of Life Could Help Select Treatment for Soft-Tissue Sarcoma
Understanding quality of life and the detrimental impact of disease progression is critical for long-term care and survival of patients with soft-tissue sarcoma.
Gemcitabine Plus Pazopanib Shows Promise in Soft-Tissue Sarcomas
Combined therapy with gemcitabine and pazopanib appears to be a viable treatment option for patients with soft-tissue sarcomas refractory to anthracycline or ifosfamide.
Regorafenib Ups Progression-Free Survival in Several Soft-Tissue Sarcomas
Regorafenib is associated with improved progression-free survival in pretreated patients with advanced refractory non-liposarcoma soft-tissue sarcomas.
Busulfan/Melphalan Associated With Longer Survival in High-Risk Ewing Sarcoma
Busulfan/melphalan high-dose chemotherapy consolidation is associated with better survival vs VAI among patients with localized high-risk Ewing sarcoma.
Drug Shows 10-Month Survival Improvement in Sarcoma
In this video, Dr. Tap discusses a randomized phase Ib/II trial that found that adding olaratumab to doxorubicin dramatically improved survival in patients with advanced soft-tissue sarcoma.
Slide Show: Gastrointestinal Stromal Tumors
This slide show features a CT image, and pathology images of gastrointestinal stromal tumors (GISTs) arising in the stomach using H&E, CD34, and c-Kit staining.
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