The US Food and Drug Administration (FDA) announced the approval of vismodegib (Erivedge), for the treatment of advanced basal cell carcinoma, the most common type of skin cancer, for patients who are not eligible for surgery or radiation, and for metastatic disease.
Using in vitro techniques and mouse models, scientists at the University of Chicago Department of Medicine and colleagues have demonstrated that downregulation of PTEN in epidermal keratinocytes predisposes skin to ultraviolet B (UVB)-induced tumorigenesis.
Older male patients who have undergone heart transplant are at a higher risk for developing squamous cell carcinoma post-surgery. In addition, certain immunosuppression agents can increase the risk of basal cell carcinoma.
A virus discovered last year in a rare form of skin cancer has also been found in people with the second most common form of skin cancer among Americans, according to researchers at the Ohio State University Comprehensive Cancer Center–James Cancer Hospital and Solove Research Institute. Their findings were published online June 25, 2009, by the Journal of Investigative Dermatology.
According to a 2005 survey conducted by the American Academy of Dermatology, 92% of the respondents understood that getting a tan from the sun is dangerous. Yet, 65% said that they think they look better when they have a tan.
Within the relatively short time that ipilimumab and vemurafenib have been commercially available, phase II data for the investigational agents nivolumab and MK-3475, for the combination of dabrafenib... More »
Eccentric darker pigmentation in this small asymptomatic lesion strongly suggests malignant melanoma. This patient had a history of non-melanoma skin cancer, but was unaware of the questionable... More »
Skin cancer is the single most common form of cancer, accounting for more than 75% of all cancer diagnoses. More than 1 million cases of squamous cell and basal cell carcinomas are diagnosed annually,... More »
This uncommon benign entity closely mimics squamous cell carcinoma, superficial basal cell carcinoma, and advanced actinic keratoses. The lichenoid keratosis does not transform into skin cancer. More »
A small punch biopsy showed basal cell carcinoma with focal hypermelanosis. The underlying erythema and punctuate superficial dark black pigmentation strongly suggested a dysplastic nevus or even a... More »
The US Food and Drug Administration (FDA) announced the approval of vismodegib (Erivedge), for the treatment of advanced basal cell carcinoma, the most common type of skin cancer, for patients who are... More »